Results 11 to 20 of about 394,846 (264)
Clinical, Cosmetic and Investigational Dermatology, 2023 Carolina Nunhez da Silva,1 Hélio Amante Miot,1 Tony Fernando Grassi,2 Luciane Alarcão Dias-Melício,2– 4 Leandro Santos,2,3 Ana Cláudia Cavalcante Espósito1 1Department of Dermatology, São Paulo State University (UNESP) - Medical School of Botucatu ...
da Silva CN +5 more
doaj +3 more sources
A novel role for myeloid endothelin-B receptors in hypertension [PDF]
European Heart Journal, 2019 Aims Hypertension is common. Recent data suggest that macrophages (Mφ) contribute to, and protect from, hypertension. Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor with additional pro-inflammatory properties.
A. Czopek +14 more
semanticscholar +8 more sources
Ligand-dependent Differences in the Internalization of Endothelin A and Endothelin B Receptor Heterodimers* [PDF]
Journal of Biological Chemistry, 2004 Endothelin-1 (ET-1) is a potent vasoactive peptide that acts on endothelin A (ETA) and endothelin B (ETB) receptors. Although both receptor subtypes are co-expressed in numerous cells, little is known about their ability to form heterodimers.
B. Gregan +7 more
semanticscholar +4 more sources
Endothelin B receptor-mediated vasoconstriction induced by endothelin A receptor antagonist [PDF]
Cardiovascular Research, 1998 The vasoconstrictor effect of endothelins (ET) is mediated by endothelin A (ETA) and endothelin B (ETB) receptors. Furthermore, ETB receptor stimulation results in release of vasodilators. Hence, ETA receptor antagonists should attenuate ET-mediated vasoconstriction. The aim of the present study was to evaluate and compare the effects of BQ-123, an ETA
Zhang, Y., Oliver, J., Horowitz, J.
openaire +4 more sources
Localization of endothelin-1 and endothelin-receptors A and B in human epididymis [PDF]
Molecular Human Reproduction, 1997 Expression of mRNA of endothelin-1 (ET-1) and its receptors, endothelin receptor A (ET-A) and endothelin receptor B (ET-B), in human epididymis was assessed by reverse transcription-polymerase chain reaction (RT-PCR). Immunohistochemistry was performed on longitudinal sections through whole normal human epididymides.
Süleyman Ergün +3 more
openaire +3 more sources
Clarifying Endothelin Type B Receptor Function [PDF]
Hypertension, 2006 Endothelin (ET) receptors have become the targets for the treatment of a variety of cardiovascular disorders and a mixed ET type A (ETA)/ET type B (ETB) receptor antagonist, bosentan, is currently being used to effectively treat pulmonary hypertension.
David M. Pollock, Markus P. Schneider
openaire +3 more sources
Targeting of endothelin receptor‐B to the neural crest [PDF]
genesis, 2008 AbstractEndothelin receptor B (Ednrb) plays a critical role in the development of melanocytes and neurons and glia of the enteric nervous system. These distinct neural crest‐derived cell types express Ednrb and share the property of intercalating into tissues, such as the intestine whose muscle precursor cells also express Ednrb.
Noah R. Druckenbrod +4 more
openaire +3 more sources
BMC Neuroscience, 2007 Background Protein kinase C (PKC) is known to be involved in the pathophysiology of experimental cerebral ischemia. We have previously shown that after transient middle cerebral artery occlusion, there is an upregulation of endothelin receptors in the ...
Vikman Petter +3 more
doaj +1 more source
Journal of the American Society of Nephrology, 2016 AKI is associated with high mortality rates and the development of CKD. Ischemia/reperfusion (IR) is an important cause of AKI. Unfortunately, there is no available pharmacologic approach to prevent or limit renal IR injury in common clinical practice ...
J. Barrera-Chimal +6 more
semanticscholar +1 more source
Frontiers in Cellular Neuroscience, 2022 Endothelin-1 (ET-1), a secreted signaling peptide, is suggested to be involved in multiple actions in various tissues including the brain, but its role in amyotrophic lateral sclerosis (ALS) remains unknown.
Yingzhen Zhang +7 more
doaj +1 more source