Results 181 to 190 of about 71,317 (233)

Central Insulin-like Growth Factor-1 Treatment Enhances Working and Reference Memory by Reducing Neuroinflammation and Amyloid Beta Deposition in a Rat Model of Sporadic Alzheimer's Disease. [PDF]

Pharmaceuticals (Basel)
Dunacka J, Grembecka B, Majkutewicz I, Wrona D.   +3 more
europepmc   +1 more source

The cholesterol‐HDL‐glucose (CHG) index and traditional adiposity markers in predicting diabetic retinopathy and nephropathy

Journal of Diabetes Investigation, EarlyView.
This study explores the association of visceral adiposity index (VAI) and lipid accumulation product (LAP), markers of visceral adiposity, with diabetic nephropathy and retinopathy. The findings revealed that VAI and LAP values were significantly elevated in diabetic nephropathy but showed no significant association with diabetic retinopathy.
Merve Çatak, Şerife Gülhan Konuk, Sema Hepsen   +2 more
wiley   +1 more source

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms. [PDF]

Oncotarget
Shyamsunder S, Lu Z, Takiar V, Waltz SE.
europepmc   +1 more source

Impact of insulin resistance on post‐stroke depression and outcomes in diabetes

Journal of Diabetes Investigation, EarlyView.
Patients with insulin resistance had a higher risk of developing post‐stroke depression after an acute cerebral infarction. The Homeostasis Model Assessment of Insulin Resistance is an independent risk factor for the development of PSD. Reducing IR may help reduce the incidence of PSD.
Lifei Tan, Yan Li, Ming Tan, Jing Gong, Jinbiao Zhang   +4 more
wiley   +1 more source

Adipose Tissue-Derived Mediators in Multiple Myeloma: Linking Obesity to Bone Disease via Inflammatory Pathways. [PDF]

Int J Mol Sci
Stroe-Ionescu AŞ, Tǎnase AD, Rotaru I, Goanțǎ JG, Pǎtraşcu AM, Boldeanu MV, Assani MZ, Siloși I, Boldeanu L, Maria DT.   +9 more
europepmc   +1 more source

Management of pregnancy with metformin: Case reports for genetic insulin resistance syndrome and a literature review for gestational and type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
We here describe perinatal glycemic management with metformin in two women with genetic insulin resistance syndrome caused by variants of the insulin receptor or phosphatidylinositol 3‐kinase (PI3K) genes. In addition, we review the literature related to the efficacy and safety of metformin treatment for gestational diabetes mellitus and type 2 ...
Kai Yoshimura, Yushi Hirota, Tetsushi Hamaguchi, Takehito Takeuchi, Tomofumi Takayoshi, Shuichiro Saito, Mariko Ueda, Seiji Nishikage, Akane Yamamoto, Naoko Hashimoto, Wataru Ogawa   +10 more
wiley   +1 more source

The 20 kDa isoform of the human growth hormone variant alters adipose and muscle gene expression differently than human growth hormone

Journal of Neuroendocrinology, EarlyView.
Abstract The 20 kDa isoform of human growth hormone variant (20K hGH‐V) (derived from the GH2 gene) has previously been shown to promote growth but lacks the diabetogenic and lactogenic activities of human GH (derived from the GH1 gene). That is, 20K hGH‐V‐treated mice have similar body size and composition to hGH‐treated mice, as well as improved ...
Jonathan A. Young, Jolie Bogart, Mat Buchman, Silvana Duran‐Ortiz, Stephen Bell, John J. Kopchick, Darlene E. Berryman, Edward O. List   +7 more
wiley   +1 more source

Effects of melatonin in polycystic ovary syndrome: is there Hippo pathway crosstalk? [PDF]

J Ovarian Res
Wang L, Jin Y, Zhi Y, Li Z, Wang M, Wang B, Wang X.   +6 more
europepmc   +1 more source

Exploring Two Different Feeding Strategies During Dry Period With Regard to Dry Matter Intake, Intermediary Metabolism and Certain Health Aspects of Dairy Cows in Germany

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Dry cow feeding plays an essential role in dairy production. Therefore, the objective of this study was to evaluate two different dry cow feeding strategies regarding dry matter intake (DMI), metabolism and health aspects of dairy cows in the first 50 days after calving.
Dana Carina Schubert, Kathrin Meetschen, Martin Pries, Sebastian Hoppe, Martin Holsteg, Hanna Rieger, Charlotte Vogel, Lothar Kreienbrock, Christian Visscher, Martin Höltershinken, Martina Hoedemaker, Josef Kamphues, Amr Abd El‐Wahab   +12 more
wiley   +1 more source

Static training improves insulin resistance in skeletal muscle of type 2 diabetic mice via the IGF-2/IGF-1R pathway. [PDF]

Sci Rep
Gan L, Chen P, Zhang Z, He X, Wu X, Chen Z, Wei Q, Wu Y.   +7 more
europepmc   +1 more source