New insights into the skeletal muscle circadian clock in ruminants. [PDF]
Wang Q +6 more
europepmc +1 more source
Developing Schwann cells acquire the ability to survive without axons by establishing an autocrine circuit involving IGF, NT-3 and PDGF-BB [PDF]
Brennan, A +4 more
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The insulin‐like growth factor system and the progression of renal complications of type 2 diabetes
Abstract Aims Chronic kidney disease is associated with dysregulation of the insulin‐like growth factor (IGF) system. Alterations in IGF bioavailability, driven by IGF binding proteins (IGFBPs), may influence the decline in renal function. However, the longitudinal relationship between baseline IGF‐I, IGF‐II, IGFBPs and progression of kidney ...
Adrian Heald +13 more
wiley +1 more source
Circulating Proinflammatory Cytokines and Soluble Cytokine Receptors as Diagnostic Biomarkers in Multiple Sclerosis. [PDF]
Bano S +4 more
europepmc +1 more source
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) increases cardiovascular and kidney disease risk. Insulin‐like growth factor 1 (IGF‐1) regulates metabolic and vascular function, but its role in long‐term cardio‐kidney outcomes (CKO) in MASLD remains unclear.
Yongin Cho +4 more
wiley +1 more source
The role of growth hormone in metastasis and angiogenesis of breast cancer. [PDF]
Alam T, Hu M, Isaacson RL.
europepmc +1 more source
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
IGFBP7 and Heart Failure: From Senescence Biomarker to Therapeutic Target. [PDF]
El-Qendouci M +5 more
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Sex differences in response to longevity interventions. [PDF]
Hajdarovic KH, Riddle NC, Webb AE.
europepmc +1 more source

