Results 141 to 150 of about 58,465 (248)

P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]

, 1998
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Barnard, EA, Brown, DA, Filippov, AK, Webb, TE   +3 more
core  

Identification of Antagonistic Action of Pyrrolizidine Alkaloids in Muscarinic Acetylcholine Receptor M1 by Computational Target Prediction Analysis

Pharmaceuticals
Pyrrolizidine alkaloids (PAs) are one of the largest distributed classes of toxins in nature. They have a wide range of toxicity, such as hepatotoxicity, pulmonary toxicity, neuronal toxicity, and carcinogenesis.
Sara Abdalfattah, Caroline Knorz, Akhtar Ayoobi, Ejlal A. Omer, Matteo Rosellini, Max Riedl, Christian Meesters, Thomas Efferth   +7 more
doaj   +1 more source

Pulmonary M1 muscarinic receptors in the rabbit

Pathophysiology, 1994
M. Yamasaki, T. Kanno, S. Shimizu, S. Matsumoto, T. Nagayama   +4 more
openaire   +2 more sources

Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.

ACS Chemical Neuroscience, 2017
Evan P. Lebois, J. Schroeder, Thomas J. Esparza, T. Bridges, C. Lindsley, P. Conn, D. Brody, J. Daniels, I. Allan, Levey   +9 more
semanticscholar   +1 more source

Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model

Neuropsychopharmacology, 2016
Ayan Ghoshal, J. M. Rook, J. Dickerson, G. N. Roop, R. Morrison, N. Jalan-Sakrikar, A. Lamsal, M. Noetzel, M. Poslusney, M. Wood, B. Melancon, S. Stauffer, Zixiu Xiang, J. Daniels, C. Niswender, Carrie K Jones, C. Lindsley, P. Conn   +17 more
semanticscholar   +1 more source

4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor.

Journal of Medicinal Chemistry, 2016
Shailesh N Mistry, M. Jörg, H. Lim, N. Vinh, P. Sexton, B. Capuano, A. Christopoulos, J. R. Lane, P. Scammells   +8 more
semanticscholar   +1 more source

A unifying hypothesis for M1 muscarinic receptor signalling in pyramidal neurons

Journal of Physiology, 2017
Sameera Dasari, C. Hill, Allan T. Gulledge   +2 more
semanticscholar   +1 more source

The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain

Neuropsychopharmacology, 2020
C. Montani, Carola Canella, A. Schwarz, Jennifer Li, G. Gilmour, A. Galbusera, K. Wafford, Daniel Gutierrez-Barragan, A. McCarthy, David B. Shaw, Karen M. Knitowski, D. McKinzie, A. Gozzi, C. Felder   +13 more
semanticscholar   +1 more source

Bile Acids Are Potential Negative Allosteric Modulators of M1 Muscarinic Receptors. [PDF]

Biomolecules
Yu W, MacKerell AD, Weber DJ, Raufman JP.   +3 more
europepmc   +1 more source

Role for the M1 Muscarinic Acetylcholine Receptor in Top-Down Cognitive Processing Using a Touchscreen Visual Discrimination Task in Mice.

ACS Chemical Neuroscience, 2015
R. Gould, Ditte Dencker, M. Grannan, M. Bubser, Xiaoyan Zhan, J. Wess, Zixiu Xiang, C. Locuson, C. Lindsley, P. Conn, C. K. Jones   +10 more
semanticscholar   +1 more source