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Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex. [PDF]
Vattino LG +4 more
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Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling. [PDF]
Drexler R +27 more
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Cholinergic system in schizophrenia: A systematic review and meta-analysis. [PDF]
Saint-Georges Z +7 more
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Muscarinic M3 receptor coupling and regulation
Life Sciences, 1997Current concepts regarding the regulation and coupling of muscarinic m3 receptors to G-proteins and various effectors are discussed. The last few years have provided much evidence that although muscarinic m1, m3 and m5 subtypes couple predominantly via pertussis toxin-insensitive G-proteins (Gq/11) to activate phosphoinositidase C (PIC), interactions ...
S R, Nahorski, A B, Tobin, G B, Willars
openaire +2 more sources
M1 and M3 muscarinic receptors
NeuroReport, 1992P-fluoro-hexahydro-sila-difenidol hydrochloride (p-F-HHSiD) (15, 30 micrograms) and pirenzepine (7.5, 15, 30 micrograms), which are highly selective M3 and M1 muscarinic antagonists, respectively, were injected intracerebroventricularly into freely moving rats.
L. IMERI +3 more
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Localization of muscarinic M3 receptor protein and M3 receptor binding in rat brain
Neuroscience, 1994A family of receptor subtypes, defined either by molecular (m1-m5) or pharmacological (M1-M4) analysis, mediates muscarinic cholinergic neurotransmission in brain. The distribution and functions of the m3 receptor protein in brain and its relation to M3 ligand binding sites are poorly understood.
Levey, Allan I. +4 more
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m3 Muscarinic Acetylcholine Receptor Regulation in the Airway
American Journal of Respiratory Cell and Molecular Biology, 2002The m3 muscarinic acetylcholine receptor (m3 mAChR) plays an important role in airway function by mediating the effects of acetylcholine on multiple airway cell types. m3 mAChRs expressed in airway smooth muscle (ASM) cells promote increased ASM tension, and, therefore, airway narrowing, in response to acetylcholine release from postganglionic ...
Charlotte K, Billington, Raymond B, Penn
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Potassium, M3 muscarinic receptors, and dopamine release
Neuroscience Research Communications, 2001AbstractThe factors determining dopamine (DA) release induced by muscarinic receptor stimulation were investigated. Carbachol facilitated DA release elicited by electrical stimulation (1Hz, 2 min). In addition, carbachol per se induced DA release (direct action); an effect dependent of potassium levels. Increasing potassium from 4.8 to 12.5 mM produced
I.S. Hoffmann +2 more
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