Results 141 to 150 of about 752,072 (376)

Spreading of EGF Receptor Activity into EGF-free Regions and Molecular Therapies of Cancer [PDF]

arXiv, 2008
The primary activation of the epidermal growth factor receptor (EGFR) has become a prominent target for molecular therapies against several forms of cancer. But despite considerable progress during the last years, many of its aspects remain poorly understood.
arxiv  

Enhanced Mechanical Properties of Injectable Chitosan–Guar Gum Hydrogel Reinforced with Bacterial Cellulose Nanofibers for Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This study presents the development and characterization of injectable nanocomposite hydrogels based on N‐succinyl chitosan, oxidized guar gum, and bacterial cellulose nanofibers. Emphasizing enhanced mechanical properties and biocompatibility, the hydrogels exhibit fast gelation, improved structural integrity, and reduced swelling. Their potential for
Raimundo Nonato Fernandes Moreira Filho, Pascale Chevallier, Silvia Rodriguez Fernandez, Maud Viallon, Matheus Xavier de Oliveira, Ana Lorena de Brito Soares, Diego Mantovani, Judith Pessoa de Andrade Feitosa, Rodrigo Silveira Vieira   +8 more
wiley   +1 more source

Static Recrystallization Simulation of Interstitial Free‐Steel by Coupling Multi‐Phase‐Field and Crystal Plasticity Model Considering Dislocation Density Distribution

Advanced Engineering Materials, EarlyView.
This study models static recrystallization in interstitial free‐steel using coupled crystal plasticity and phase‐field simulations. The method directly links heterogeneous dislocation density to nucleation site prediction, eliminating reliance on empirical assumptions.
Alireza Rezvani, Ramin Ebrahimi, Ebad Bagherpour   +2 more
wiley   +1 more source

Characterization of the binding properties and retrograde axonal transport of a monoclonal antibody directed against the rat nerve growth factor receptor

Journal of Cell Biology, 1985
We have demonstrated in vitro and in vivo the specific binding of a monoclonal antibody to the rat nerve growth factor (NGF) receptor. Previous work had shown that this antibody, designated 192-IgG, does not compete with NGF for binding to the NGF ...
M. Taniuchi, E. Johnson
semanticscholar   +1 more source

Defining the organizational structure of dopamine and muscarninic acetylcholine receptors [PDF]

, 2015
No abstract ...
Alvarez-Curto, Elisa, Caltabiano, Gianluigi Caltabiano, Liste, María José Varela, Marsango, Sara, Milligan, Graeme   +4 more
core   +1 more source

Profilometry‐Based Indentation Plastometry Testing of Tungsten at High Temperature

Advanced Engineering Materials, EarlyView.
Profilometry‐based indentation plastometry (PIP) allows extraction of stress‐strain curves from indent profiles. Tungsten is of industrial interest but is brittle at room temperature. It does plastically deform at higher temperatures. Excellent agreement is obtained between the two techniques in this regime, but PIP also gives plasticity ...
James Rees Miller, Philip John McKeown, Hillary Qiu, Trevor William Clyne   +3 more
wiley   +1 more source

Stochastic models of the binding kinetics of VEGF-A to VEGFR1 and VEGFR2 in endothelial cells [PDF]

arXiv, 2016
Vascular endothelial growth factor receptors (VEGFRs) are receptor tyrosine kinases (RTKs) that regulate proliferation, migration, angiogenesis and vascular permeability of endothelial cells. VEGFR1 and VEGFR2 bind vascular endothelial growth factors (VEGFs), inducing receptor dimerisation and activation, characterised by phosphorylation of tyrosine ...
arxiv  

Residual Stress States in Microstructurally Graded PBF–LB/M Austenitic Steel Components

Advanced Engineering Materials, EarlyView.
This study examines microstructurally graded 316L rectangular tube profiles fabricated via PBF–LB/M using a dual‐laser system. A 1 kW top‐hat and a 400 W Gaussian laser create distinct grain sizes and crystallographic texture. Mechanical properties are linked to microstructural evolution driven by processing conditions.
Nico Möller, Florian Loebich, Thomas Wegener, Julia Richter, Jens Gibmeier, Thomas Niendorf   +5 more
wiley   +1 more source

Expressão de neurotrofinas e de seus receptores no osteossarcoma primário.

Revista do Colégio Brasileiro de Cirurgiões, 2019
RESUMO Objetivo: determinar a expressão de neurotrofinas e seus receptores tirosina quinases em pacientes com osteossarcoma (OS) e sua correlação com desfechos clínicos.
Bruno Pereira Antunes, Ricardo Gehrke Becker, André Tesainer Brunetto, Bruno Silveira Pavei, Caroline Brunetto de-Farias, Luís Fernando da Rosa Rivero, Julie Francine Cerutti Santos, Bruna Medeiros de-Oliveira, Lauro José Gregianin, Rafael Roesler, Algemir Lunardi Brunetto, Fernando Pagnussato, Carlos Roberto Galia   +12 more
doaj   +1 more source

Mesoporous Silica Microspheres by Super‐Fast Alkaline Etching of Micrometer‐Sized Stöber Particles

Advanced Engineering Materials, EarlyView.
Microscale silica particles are prepared along with a modified, scalable Stöber synthesis using the continuous addition of tetraethoxy silane to an ethanolic solution of ammonia with KCl. Etching with hydroxide ions at 95 °C gave porous analogs within minutes. Monodisperse particles are isolable in high yield after precipitation in ethanol.
Adrian Vaghar, Georgij Jegorenkov, Gerrit A. Luinstra   +2 more
wiley   +1 more source