Results 11 to 20 of about 752,072 (376)

Vagus nerve stimulation is a potential treatment for ischemic stroke

open access: yesNeural Regeneration Research, 2023
Microglia are the brain’s primary innate immune cells, and they are activated and affect pro-inflammatory phenotype or regulatory phenotype after ischemic stroke.
Yi-Lin Liu   +4 more
doaj   +1 more source

Morphofunctional Characterization of Different Tissue Factors in Congenital Diaphragmatic Hernia Affected Tissue

open access: yesDiagnostics, 2021
Congenital diaphragm hernia (CDH) is a congenital disease that occurs during prenatal development. Although the morbidity and mortality rate is rather significant, the pathogenesis of CDH has been studied insignificantly due to the decreased ...
Ricards Kaulins   +3 more
doaj   +1 more source

Balancing neurotrophin pathway and sortilin function: its role in human disease [PDF]

open access: yes, 2021
Neurotensin receptor-3 or sortilin is a vacuolar protein sorting 10 protein domain (Vps10p) has been firstly discovered in the human brain, it acts as receptor or co-receptor of the cell and traffics different proteins within the cell.
Acha-Sagredo, A.   +9 more
core   +1 more source

Nerve growth factor binding domain of the nerve growth factor receptor. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1991
A structural analysis of the rat low-affinity nerve growth factor (NGF) receptor was undertaken to define the NGF binding domain. Mutant NGF receptor DNA constructs were expressed in mouse fibroblasts or COS cells, and the ability of the mutant receptor to bind NGF was assayed.
Catherine M. Bitler   +3 more
openaire   +3 more sources

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects

open access: yesNeural Regeneration Research, 2023
Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin   +7 more
doaj   +1 more source

Nerve Growth Factor Signaling and Its Contribution to Pain

open access: yesJournal of Pain Research, 2020
Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation, and survival of sympathetic and sensory afferent neurons during development.
P. Barker   +4 more
semanticscholar   +1 more source

The effects of painless nerve growth factor on human microglia polarization

open access: yesFrontiers in Cellular Neuroscience, 2022
Previous studies in the rat suggest that microglial cells represent a potential druggable target for nerve growth factor (NGF) in the brain. The painless human Nerve Growth Factor (hNGFp) is a recombinant mutated form of human nerve growth factor (hNGF ...
Lucia Lisi   +8 more
doaj   +1 more source

Seasonal Expression of NGF and Its Cognate Receptors in the Ovaries of Grey Squirrels (Sciurus carolinensis)

open access: yesAnimals, 2020
The grey squirrel is an invasive alien species that seriously threatens the conservation of the native red squirrel species. With the aim of characterizing the reproductive physiology of this species due to its great reproductive success, the function of
Margherita Maranesi   +9 more
doaj   +1 more source

Acetyl-11-keto-beta-boswellic acid promotes sciatic nerve repair after injury: molecular mechanism

open access: yesNeural Regeneration Research, 2022
Previous studies showed that acetyl-11-keto-beta-boswellic acid (AKBA), the active ingredient in the natural Chinese medicine Boswellia, can stimulate sciatic nerve injury repair via promoting Schwann cell proliferation. However, the underlying molecular
Yao Wang   +6 more
doaj   +1 more source

Bile acids induce visceral hypersensitivity via mucosal mast cell–to–nociceptor signaling that involves the farnesoid X receptor/nerve growth factor/transient receptor potential vanilloid 1 axis

open access: yesThe FASEB Journal, 2018
Increased colonic bile acid (BA) exposure, frequent in diarrhea‐predominant irritable bowel syndrome (IBS‐D), can affect gut function. Nerve growth factor (NGF) is implicated in the development of visceral hyper‐sensitivity (VH). In this study, we tested
Wen-Ting Li   +6 more
semanticscholar   +1 more source

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