Results 271 to 280 of about 284,983 (313)
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Journal of Neurochemistry, 1987
Abstract: We have used biologically active derivatives of β‐nerve growth factor (NGF), modified by biotinylation via carboxyl groups, to target the specific binding of liposomes to cultured rat and human tumor cells bearing NGF receptors. Liposomes, to be used for targeting, were prepared by conjugating streptavidin to phospholipid amino groups on ...
M B, Rosenberg +2 more
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Abstract: We have used biologically active derivatives of β‐nerve growth factor (NGF), modified by biotinylation via carboxyl groups, to target the specific binding of liposomes to cultured rat and human tumor cells bearing NGF receptors. Liposomes, to be used for targeting, were prepared by conjugating streptavidin to phospholipid amino groups on ...
M B, Rosenberg +2 more
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European Journal of Oral Sciences, 2012
Nerve growth factor (NGF) is a pluripotent mediator that is present in a range of human tissues. Nerve growth factor was originally considered important only in neuronal homeostasis and pathophysiology, but later it was also implicated in the pathophysiology of inflammation, epithelial differentiation, and wound healing. In this study, the distribution
Elsebeth P, Naesse +4 more
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Nerve growth factor (NGF) is a pluripotent mediator that is present in a range of human tissues. Nerve growth factor was originally considered important only in neuronal homeostasis and pathophysiology, but later it was also implicated in the pathophysiology of inflammation, epithelial differentiation, and wound healing. In this study, the distribution
Elsebeth P, Naesse +4 more
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Nerve growth factor receptor role on rabbit sperm storage
Theriogenology, 2020The influence of NGF in male reproduction in some animal species and humans has already been assessed. Many of these effects are mediated by the distribution and abundance of tropomyosin receptor kinase A (TrKA) and p75 neurotrophin (p75NTR) receptors on sperm cells.
Cesare, Castellini +7 more
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The Membrane Receptor for Nerve Growth Factor
1991Receptors for mammalian growth factors are integral membrane proteins designed to have multiple functions for communicating with other cells and for intracellular signal transduction. These cell surface proteins have binding sites for the ligand that face the external environment and also an effector site that generates a biological signal within the ...
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European Journal of Neuroscience, 1990
AbstractSensory neurons of the adult rat dorsal root ganglion (DRG) can be maintained in culture in the absence of nerve growth factor (NGF). We have thus used dissociated cultures of these neurons to study effects of NGF on the regulation of expression of mRNA encoding the nerve growth factor receptor (NGF‐R).
R. M., Lindsay +6 more
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AbstractSensory neurons of the adult rat dorsal root ganglion (DRG) can be maintained in culture in the absence of nerve growth factor (NGF). We have thus used dissociated cultures of these neurons to study effects of NGF on the regulation of expression of mRNA encoding the nerve growth factor receptor (NGF‐R).
R. M., Lindsay +6 more
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Gerontology, 2003
<i>Background:</i> Nerve growth factor (NGF), discovered because of its action on cells in the peripheral and the central nervous system, is now known to act also on immune cells in developing and adult subjects. Whether peripheral lymphocytes of aged subjects are responsive to this molecule is less clear.
Antonelli A, Bracci Laudiero L, Aloe L
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<i>Background:</i> Nerve growth factor (NGF), discovered because of its action on cells in the peripheral and the central nervous system, is now known to act also on immune cells in developing and adult subjects. Whether peripheral lymphocytes of aged subjects are responsive to this molecule is less clear.
Antonelli A, Bracci Laudiero L, Aloe L
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Nerve Growth Factor Synthesis and Nerve Growth Factor Receptor Expression in Neural Development
1991Publisher Summary This chapter describes nerve growth factor (NGF) in the context of the neurotrophic theory. It also discusses its implications for understanding the molecular basis of neuron–target interactions in the developing nervous system. Since its discovery, NGF has been the prototype of a class of proteins termed “neurotrophic factors” that
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The expression of growth factor receptors during nerve regeneration
Restorative Neurology and Neuroscience, 1990Growth factors and their receptors play a central role in the regulation of normal and injury-induced regenerative cell growth. In this article we review the data on the expression of growth factor receptors for β-nerve growth factor, platelet-derived growth factor and serum transferrin during regeneration following peripheral nerve injury.
Raivich, G. +3 more
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Regulation of the Synthesis of Nerve Growth Factor and Nerve Growth Factor Receptor
1988The importance of Nerve Growth Factor (NGF) for the development and the maintenance of differentiated properties of peripheral sympathetic and neural crest- derived sensory neurons as well as for basal forebrain cholinergic neurons is well established (cf Levi-Montalcini & Angeletti, 1968; Greene & Shooter, 1980; Thoenen & Barde, 1980; Thoenen et al ...
R. Heumann +7 more
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THE RECEPTORS FOR NERVE GROWTH FACTOR AND OTHER NEUROTROPHINS
Annual Review of Biochemistry, 1993OVERVIEW .. . . . . . . . . . .. . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823 HISTORICAL ASPECTS . . . . . . . .. . . . . . . . . .. . . . . . . . . . .. . . . . . . . 825 MOLECULAR PROPERTIES . . . . . . . . . . . . . . . . ... . . . . .. . . .... . . . 827 Low-Molecular-Weight Receptor (LNGFR; p75) . l.:' . • . . . . . . . . . .
S, Raffioni, R A, Bradshaw, S E, Buxser
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