Results 281 to 290 of about 284,983 (313)
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Nerve Growth Factor Receptor Immunoreactivity in Breast Cancer Patients
Cancer Investigation, 2001Nerve growth factor receptor (NGF-R) has been shown to have antiproliferative, differentiative, or apoptotic effects on some types of tumor cells, whereas in others it may have mitogenic activity. The immunohistochemical distribution of NGF-R was analyzed in a series of tissue samples from breast cancer patients and its relationship with other clinical
ARAGONA, Marcello +7 more
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Nerve Growth Factor Receptors and Signaling in Breast Cancer
Current Cancer Drug Targets, 2004Nerve growth factor (NGF) has long been known for its effects on neuronal cell survival and differentiation. This prototypical neurotrophic factor stimulates neurons through two distinct classes of membrane receptors: the TrkA tyrosine kinase receptor, and the tumor necrosis factor receptor family member p75NTR, also known as the common neurotrophin ...
Dollé, Laurent +5 more
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Effect of retinoic acid on nerve growth factor receptors
Cell and Tissue Research, 1987Retinoic acid (RA), a naturally occurring metabolite of vitamin A, increased the number of receptors for nerve growth factor (NGF) in cultured human neuroblastoma cells (LA-N-1), as indicated by an immunofluorescence assay of cell surface receptors and by specific binding of 125I-NGF to solubilized receptors. Analysis of 125I-NGF binding showed that RA
B E, Haskell +3 more
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Nerve growth factor receptors in the central nervous system
Experimental Neurology, 1988Nerve growth factor (NGF) is well known to be involved in the development, survival, and maintenance of sympathetic and neural crest-derived sensory neurons in the peripheral nervous system. Over the last 10-15 years, however, the role of NGF as a necessary trophic substrate for magnocellular cholinergic neurons in the central nervous system (CNS) has ...
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Nerve Growth Factor (NGF) Receptors in Male Reproductive Organs
1997In addition to its essential role for the survival, development and differentiation of neurons of the central and peripheral nervous systems, nerve growth factor (NGF) seems to exert also a variety of nonneurotrophic activities. In particular, there is considerable evidence for crucial functions of NGF within the male reproductive system.
D, Müller +3 more
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The Nerve Growth Factor Receptor: Biochemical and Structural Analysis
1989Publisher Summary This chapter reviews the biochemical characterization of the human nerve growth factor (NGF) receptor and the expression and molecular cloning of the receptor after gene transfer into heterologous cells. It also discusses the structural features of the receptor in relation to its many functional responses.
B L, Hempstead, M V, Chao
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The heterogeneity of nerve growth factor receptors.
Progress in clinical and biological research, 1980Chick embryonic sensory ganglia cells have two specific nerve growth factor receptors, site I and site II receptors, whose binding affinities differ by two orders of magnitude. As judged by both steady state binding and kinetic data, the two receptors behave independently.
A, Sutter +3 more
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Epidermal growth factor receptor not equal to nerve growth factor.
Neurobiology of aging, 1989I am perplexed by the authors' complete lack of definition of neurotrophic factors. The agents Butcher and Woolf want to blame are neurite promoting factors, not neurotrophic factors. Treatment of Alzheimer's disease with NGF antagonists might instead exacerbate the death of both basal forebrain neurons and their cortical target neurons, accelerating ...
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Cancer treatment and survivorship statistics, 2022
Ca-A Cancer Journal for Clinicians, 2022Kimberly D Miller +2 more
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