Results 31 to 40 of about 752,072 (376)
Biodegradable magnesium wire promotes regeneration of compressed sciatic nerves
Neural Regeneration Research, 2016 Magnesium (Mg) wire has been shown to be biodegradable and have anti-inflammatory properties. It can induce Schwann cells to secrete nerve growth factor and promote the regeneration of nerve axons after central nervous system injury. We hypothesized that
Bo-han Li, Ke Yang, Xiao Wang
doaj +1 more source
Cargo binding promotes KDEL receptor clustering at the mammalian cell surface [PDF]
Sci. Rep. 6, 28940, 2016, 2017 Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from chemotactic receptors in bacteria to ...
arxiv +1 more source
Neural Regeneration Research, 2016 Delayed ischemic neurologic deficit after subarachnoid hemorrhage results from loss of neural cells. Nerve growth factor and its receptor TrkA may promote regeneration of neural cells, but their expression after subarachnoid hemorrhage remains unclear ...
Jin-ning Song +6 more
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). [PDF]
PLoS Pathogens, 2013 Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25206) to yield SNAP25197.
Birgitte P S Jacky +12 more
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Journal of Investigative Dermatology, 1994 Keratinocytes, a key cellular component both for homeostasis and pathophysiologic processes of the skin, secrete a number of cytokines and are stimulated by several growth factors. Nerve growth factor (NGF) is synthesized in the skin and basal keratinocytes express the low-affinity nerve growth factor receptor (NGF-R).
PINCELLI, Carlo +9 more
openaire +5 more sources
Identification of a conserved protein motif in a group of growth factor receptors [PDF]
, 1990 Residues 370–383 (helix C) of the human nerve growth factor receptor (NGF-R) are highly similar to the sequence of the 14 residue wasp toxin, mastoparan.
Feinstein, Douglas L., Larhammar, Dan
core +1 more source
Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis
Nature Communications, 2023 Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking and climbing stairs. Piezo2 has been implicated in the development of mechanical pain, but the mechanisms
Alia M. Obeidat +10 more
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Nerve Growth Factor Induces Proliferation and Aggressiveness in Prostate Cancer Cells
Cancers, 2019 Resistance to hormone therapy and disease progression is the major challenge in clinical management of prostate cancer (PC). Drugs currently used in PC therapy initially show a potent antitumor effects, but PC gradually develops resistance, relapses and ...
M. Di Donato +3 more
semanticscholar +1 more source
A Systemic Receptor Network Triggered by Human cytomegalovirus Entry [PDF]
Advances in Virology Volume 2011 (2011), Article ID 262080, 11
pages, 2010 Virus entry is a multistep process that triggers a variety of cellular pathways interconnecting into a complex network, yet the molecular complexity of this network remains largely unsolved. Here, by employing systems biology approach, we reveal a systemic virus-entry network initiated by human cytomegalovirus (HCMV), a widespread opportunistic ...
arxiv +1 more source
BMC Medical Genetics, 2018 Background Despite the important role of the nerve growth factor in the survival and maintenance of neurons in ischemic stroke, data regarding the relationships between variations in the encoding gene and stroke are lacking.
Ani Stepanyan +4 more
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