Results 31 to 40 of about 284,983 (313)

Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]

, 2017
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M, Amor S, Amor S, Appel SH, Bankston AN, Biber K, Biran V, Borsook D, Brenner T, Brooks TA, Buchanan MM, Bulanova E, Burnstock G, Calcia MA, Castellheim A, Chan-Ling T, Chen YJ, Choudhuri K, Christophi GP, Christy AL, Compston A, Conti P, Corrigan F, Cristino L, Cunningham C, Dirckx M, Donath MY, Done JD, D’Agostino G, Eckenhoff RG, Eggen BJ, Ellis A, Engler H, Ertürk A, Eskander MA, Esposito P, Fonken LK, Forsythe P, Freeman LC, Fullerton JN, Gao YJ, Gaudenzio N, Geppetti P, Grace PM, Grakoui A, Gregory GD, Griffin RS, Guerreiro R, Gunin AG, Hagiyama M, Hains LE, Hanisch UK, Harcha PA, Harvey GK, Hayashi R, Heneka MT, Hickman SE, Hsieh CL, Hu W, Héron A, Iadecola C, Ito A, Jay GW, Jensen TS, Ji RR, Jin Y, Jin Y, Juremalm M, Kajihara Y, Kalesnikoff J, Kalichman MW, Kamm CP, Kerstman E, Kobayashi K, Kolbinger F, Koshinaga M, Kwon C, Lange C, Lapilover EG, Laura Facci, Le Thuc O, Leon A, Levy D, Li M, Li X, Liew FY, Lozada A, Lull ME, Luongo L, Manocha GD, Marchi N, Martini R, Maslinska D, Mate I, Matsuda H, Mattila OS, McGeer PL, Medeiros R, Medic N, Medic N, Michaloudi H, Michaud M, Millan MJ, Miller G, Milligan ED, Monks CR, Morena Zusso, Myers RR, Nakae S, Nakajima A, Nathan C, Nave KA, Nelissen S, Nguyen M, Norden DM, Noriega DB, Old EA, Orr AG, Osipchuk Y, Osterberg A, Park CK, Parvathenani LK, Patti GJ, Peferoen L, Peferoen LA, Pekny M, Pelisch N, Perry VH, Perry VH, Pietro Giusti, Prinz M, Prussin C, Punzo D, Ramlackhansingh AF, Ransohoff RM, Rapp JH, Rawji KS, Riedel B, Rivat C, Rosa AC, Sakamoto A, Sastre M, Sayed BA, Silver R, Silverman AJ, Sivanandam TM, Skaper SD, Skaper SD, Skaper SD, Skaper SD, Skaper SD, Skuljec J, Smith BH, Smith JA, Sospedra M, Stephen D. Skaper, Streit WJ, Suurmond J, Terrando N, Thacker MA, Theoharides TC, Theoharides TC, Theoharides TC, Theoharides TC, Theoharides TC, Ulmann L, van Hecke O, Varma R, von Büdingen HC, Vyas H, Wang M, Wang Y, Wardlaw AJ, Watkins LR, Wohleb ES, Xie F, Young KM, Yuan H, Zarpelon AC, Zeis T, Zhang H, Zhang S, Zhang ZG, Zuo Y   +183 more
core   +1 more source

Modeling Glioma Growth and Invasion in Drosophila melanogaster

Neoplasia: An International Journal for Oncology Research, 2009
Glioblastoma is the most common and most malignant intrinsic human brain tumor, characterized by extensive invasion and proliferation of glial (astrocytic) tumor cells, frequent activation of tyrosine kinase receptor signaling pathways, relative ...
Hanna Teresa Witte, Astrid Jeibmann, Christian Klämbt, Werner Paulus   +3 more
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila, Chernov, Andrei V, Dolkas, Jennifer, Hullugundi, Swathi K, Remacle, Albert G, Shubayev, Veronica I, Strongin, Alex Y   +6 more
core   +2 more sources

Expression and Function of Nerve Growth Factor and Nerve Growth Factor Receptor on Cultured Keratinocytes

Journal of Investigative Dermatology, 1994
Keratinocytes, a key cellular component both for homeostasis and pathophysiologic processes of the skin, secrete a number of cytokines and are stimulated by several growth factors. Nerve growth factor (NGF) is synthesized in the skin and basal keratinocytes express the low-affinity nerve growth factor receptor (NGF-R).
PINCELLI, Carlo, C. Sevignani, MANFREDINI, Rossella, GRANDE, Alexis, F. Fantini, L. Bracci Laudiero, L. Aloe, FERRARI, Sergio, COSSARIZZA, Andrea, GIANNETTI, Alberto   +9 more
openaire   +4 more sources

Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke

BMC Medical Genetics, 2018
Background Despite the important role of the nerve growth factor in the survival and maintenance of neurons in ischemic stroke, data regarding the relationships between variations in the encoding gene and stroke are lacking.
Ani Stepanyan, Roksana Zakharyan, Arsen Simonyan, Gohar Tsakanova, Arsen Arakelyan   +4 more
doaj   +1 more source

Drosophila Neurotrophins Reveal a Common Mechanism for Nervous System Formation [PDF]

, 2008
Neurotrophic interactions occur in Drosophila, but to date, no neurotrophic factor had been found. Neurotrophins are the main vertebrate secreted signalling molecules that link nervous system structure and function: they regulate neuronal survival ...
Aberle, Alcantara, Alicia Hidalgo, Altar, Arancio, Arenas, Arendt, Armstrong, Bangfu Zhu, Barde, Barres, Beck, Belluardo, Ben Sutcliffe, Benito-Gutierrez, Bergmann, Bergner, Blum, Booth, Bossing, Bothwell, Broihier, Buj-Bello, Burke, Campos, Cash, Chao, Chen, Chevrel, Chun-Jing Gu, Coen, Collette, Collins, Conover, Crowley, Davies, Dearborn, DeLotto, Denes, Dong, Enokido, Ernfors, Ernfors, Fischbach, Freudenthal, Gangloff, Geddes, Halfon, Halfon, Hallbö, Hashimoto, Hemmrich, Henderson, Hidalgo, Hofer, Hu, Huang, Hyman, Inamori, Jaaro, Jacob, Jacobs, Janine C Fenton, Jenny A Pennack, Keishishian, Keishishian, Kenji Mizuguchi, Kirstein, Klein, Landgraf, Landgraf, Landgraf, Landgraf, Landgraf, Learte, Lee, Levi-Montalcini, Ligoxigakis, Liu, Liu, Lu, Ma, Manjon, Manuel G Forero, Martinowich, Mattson, McCabe, Means, Memet, Michael Bate, Minichiello, Mizuguchi, Mizuguchi, Morisato, Moroz, Morris, Noordermeer, Odden, Oppenheim, Oppenheim, Ormond, Parker, Peter McQuilton, Pezet, Putnam, Rogulja-Ortmann, Rose, Roux, Rubin, Sali, Scarabelli, Schmidt, Schwartz, Schweigreiter, Sendtner, Shi, Silos-Santiago, Sink, Sink, Snider, Sofroniew, Sonnenfeld, Sossin, Stadelmann, Staniszewska, Stemerdink, Tauszig, van Kesteren, Venter, Wang, Weber, Weber, White, Wright, Xiong, Zhou, Zweifel   +136 more
core   +4 more sources

Modified insulin-like growth factor 1 containing collagen-binding domain for nerve regeneration

Neural Regeneration Research, 2018
Insulin-like growth factor 1 (IGF-1) is a potential nutrient for nerve repair. However, it is impractical as a therapy because of its limited half-life, rapid clearance, and limited target specificity.
Jian-an Li, Chang-fu Zhao, Shao-jun Li, Jun Zhang, Zhen-hua Li, Qiao Zhang, Xiao-yu Yang, Chun-fang Zan   +7 more
doaj   +1 more source

Expression and Signaling Pathways of Nerve Growth Factor (NGF) and Pro-NGF in Breast Cancer: A Systematic Review

Current Oncology, 2022
Breast cancer represents the most common type of cancer and is the leading cause of death due to cancer among women. Thus, the prevention and early diagnosis of breast cancer is of primary urgency, as well as the development of new treatments able to ...
Francesco Bruno, Domenico Arcuri, Francesca Vozzo, Antonio Malvaso, Alberto Montesanto, Raffaele Maletta   +5 more
doaj   +1 more source

Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]

, 2013
Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core   +1 more source

15d-Prostaglandin J2 Enhancement of Nerve Growth Factor–Induced Neurite Outgrowth Is Blocked by the Chemoattractant Receptor– Homologous Molecule Expressed on T-Helper Type 2 Cells (CRTH2) Antagonist CAY10471 in PC12 Cells

Journal of Pharmacological Sciences, 2010
The chemoattractant receptor–homologous molecule expressed on T-helper type 2 cells (CRTH2) is the most recently identified prostaglandin (PG) receptor for both PGD2 and 15-deoxy-Δ12,14-PGJ2 (15d-PGJ2).
Michiyoshi Hatanaka, Norihiro Shibata, Norihito Shintani, Ryota Haba, Atsuko Hayata, Hitoshi Hashimoto, Akemichi Baba   +6 more
doaj   +1 more source