Results 181 to 190 of about 144,656 (207)

Dysregulation of Platelet-Derived Growth Factor β-Receptor Expression by ΔNp73 in Neuroblastoma

Molecular Cancer Research, 2009
Abstract We have previously characterized how p53 family proteins control the transcriptional regulation of the platelet-derived growth factor β-receptor (PDGFRB) and found that ΔNp73α, acting dominant-negatively to p53 and p73, can upregulate PDGFRB promoter activity.
Daniel, Wetterskog, Abtin, Moshiri, Toshinori, Ozaki, Hidetaka, Uramoto, Akira, Nakagawara, Keiko, Funa   +5 more
openaire   +2 more sources

Transforming growth factor-beta 1 regulates platelet-derived growth factor receptor beta subunit in human liver fat-storing cells.

Hepatology (Baltimore, Md.), 1995
Activated liver fat-storing cells (FSC) are known to play a key role in the development of liver fibrosis. An important element in FSC activation process is the increased expression of receptors for platelet-derived growth factor (PDGF), a potent mitogen for FSC.
PINZANI, MASSIMO, GENTILINI, ALESSANDRA, A. Caligiuri, R. DeFranco, PELLEGRINI, GIULIA, MILANI, STEFANO, MARRA, FABIO, GENTILINI, PAOLO   +7 more
openaire   +2 more sources

A Rapid Bioassay for Platelet–Derived Growth Factor β-Receptor Tyrosine Kinase Function

Bio/Technology, 1994
We have extended a melanophore-based bioassay for G-protein coupled receptors to include the functional expression of the murine platelet-derived growth factor (PDGF) beta-receptor. The homodimeric ligand PDGF-BB induced activation of the transiently expressed receptor in melanophore cells.
G F, Graminski, M R, Lerner
openaire   +2 more sources

Platelet-derived growth factor receptor (beta-subunit) immunoreactivity in soft tissue tumors.

Laboratory investigation; a journal of technical methods and pathology, 1992
Using a well characterized monoclonal antibody (PR7212) to the beta-subunit of the platelet-derived growth factor receptor (PDGF-R(beta) and the avidin-biotin peroxidase method on frozen sections, we analyzed PDGF-R(beta) expression in 71 nonepithelial lesions as well as normal mesenchymal tissues.
C, Palman, D F, Bowen-Pope, J J, Brooks
openaire   +1 more source

[Expression of platelet derived growth factor receptor-beta in fibroblasts of keloid].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2003
To investigate the expression and distribution of platelet derived growth factor receptor-beta(PDGFR-beta) in normal skin and keloid and to discuss its biological function in keloid formation.1. To detect the expression and distribution of PDGFR-beta in normal skin and keloid tissue by immunohistochemistry; 2. To detect the receptor expression in vitro
Q X, Shang, R, Yuan, W, Wang
openaire   +1 more source

Cancer treatment and survivorship statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Kimberly D Miller, Leticia M Nogueira, Angela B Mariotto   +2 more
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions

Ca-A Cancer Journal for Clinicians, 2023
Balazs Dome
exaly  

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly