Results 11 to 20 of about 79,696 (126)

Platelet-Derived Growth Factor Receptor Beta: A Novel Urinary Biomarker for Recurrence of Non-Muscle-Invasive Bladder Cancer [PDF]

PLoS ONE, 2014
Non-muscle-invasive bladder cancer (NMIBC) is one of the most common malignant tumors in the urological system with a high risk of recurrence, and effective non-invasive biomarkers for NMIBC relapse are still needed.
Jia-yu Feng, Weifeng He, Yajun Song, Ying Wang, R. Simpson, Xiao-rong Zhang, G. Luo, Jun Wu, Chibing Huang   +8 more
semanticscholar   +2 more sources

Platelet-Derived Growth Factor Receptor β Is Critical for Zebrafish Intersegmental Vessel Formation [PDF]

PLoS ONE, 2010
Platelet-derived growth factor receptor beta (PDGFRbeta) is a tyrosine kinase receptor known to affect vascular development. The zebrafish is an excellent model to study specific regulators of vascular development, yet the role of PDGF signaling has not been determined in early zebrafish embryos.
Wiens, Katie M., Lee, Hyunju, Shimada, Hiroyuki, Metcalf, Anthony E., Chao, Michael, Lien, Ching-Ling   +5 more
openaire   +6 more sources

GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex

Biomolecules, 2023
Growth differentiation factor-15 (GDF-15) is proposed to be strongly associated with several cardiovascular diseases, such as heart failure and atherosclerosis.
Baikang Xie, Wenjing Tang, Shuang Wen, Fen Chen, Chao Yang, Min Wang, Yong Yang, Wei Liang   +7 more
doaj   +1 more source

High tumor cell platelet‐derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma

The Journal of Pathology: Clinical Research, 2021
Malignant pleural mesothelioma (MPM) has a rich stromal component containing mesenchymal fibroblasts. However, the properties and interplay of MPM tumor cells and their surrounding stromal fibroblasts are poorly characterized.
Hely Ollila, Juuso Paajanen, Henrik Wolff, Ilkka Ilonen, Eva Sutinen, Katja Välimäki, Arne Östman, Sisko Anttila, Eeva Kettunen, Jari Räsänen, Olli Kallioniemi, Marjukka Myllärniemi, Mikko I Mäyränpää, Teijo Pellinen   +13 more
doaj   +1 more source

Osteoclasts control osteoblast chemotaxis via PDGF-BB/PDGF receptor beta signaling. [PDF]

PLoS ONE, 2008
Bone remodeling relies on the tightly regulated interplay between bone forming osteoblasts and bone digesting osteoclasts. Several studies have now described the molecular mechanisms by which osteoblasts control osteoclastogenesis and bone degradation ...
Maria Arantzazu Sanchez-Fernandez, Anne Gallois, Thilo Riedl, Pierre Jurdic, Bernard Hoflack   +4 more
doaj   +1 more source

Direct interaction between Shc and the platelet-derived growth factor beta-receptor. [PDF]

Journal of Biological Chemistry, 1994
The Src homology 2 (SH2) domain-containing Shc proteins p52shc and p46shc become phosphorylated upon activation of several tyrosine kinases and are implicated in mitogenic signal transduction. Ligand stimulation of the platelet-derived growth factor (PDGF) beta-receptor leads to autophosphorylation of tyrosine residues, which is known to mediate ...
C H Heldin, Koutaro Yokote, Lena Claesson-Welsh, Klaus Hansen, Seijiro Mori, J McGlade, T Pawson   +6 more
openaire   +2 more sources

Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells [PDF]

Oncogene, 2003
The Ewing's sarcoma family of tumors (ESFT) contain a translocation, t(11;22), which results in the novel oncogenic fusion protein EWS/FLI1. Platelet-derived growth factors (PDGF) and their receptors (PDGFR) are involved in the induction and proliferation of numerous solid tumors and are the potential candidates for novel targeted antitumor therapy ...
Antonino Passaniti, Maria Tsokos, Melinda S. Merchant, Jeffrey A. Toretsky, Chen-Chih J Sun, Aykut Üren, Marc Ladanyi, Crystal L. Mackall, P B Illei, Y Sun, Michele Vitolo   +10 more
openaire   +3 more sources

Evaluation of serum platelet-derived growth factor receptor-ß and brain-derived neurotrophic factor levels in microvascular angina

Anatolian Journal of Cardiology, 2020
Objective: Microvascular angina (MVA) is a coronary microcirculation disease. Research on microcirculatory dysfunction has revealed several biomarkers involved in the etiopathogenesis of MVA.
Gamze Aslan, Veli Polat, Evin Bozcali, Mustafa Hakan Şahin, Nurcan Çetin, Dilek Ural   +5 more
doaj   +1 more source

A report of an unusual case of pediatric eosinophilia associated with platelet-derived growth factor receptor-beta rearrangement

Indian Journal of Medical and Paediatric Oncology, 2020
Eosinophilia is a common finding in the pediatric age group. While the majority of mild eosinophilia cases are benign and due to reactive causes, persistent hypereosinophilia is uncommon and requires prompt clinical evaluation because of the potential ...
Abdul Wajid Moothedath, Debasish Sahoo, Rachna Seth, Jagdish Prasad Meena, Aditya Kumar Gupta   +4 more
doaj   +1 more source

Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans. [PDF]

Journal of Clinical Investigation, 1993
The expression and localization of PDGF beta receptors and PDGF-AB/BB in human healing wounds was evaluated by immunohistochemical techniques and in situ hybridization. Expression of PDGF beta receptor protein and PDGF-AB/BB were analyzed in wound margin biopsies using the PDGFR-B2 and PDGF 007 antibodies.
Keiko Funa, Christian Sundberg, C Reuterdahl, Kristofer Rubin, B Gerdin   +4 more
openaire   +3 more sources