Results 51 to 60 of about 144,656 (207)
High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]
, 2015 Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono) +3 more
core +2 more sources
Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease [PDF]
, 2010 Because regional blood flow increases in association with the increased metabolic demand generated by localised increases in neural activity, functional imaging researchers often assume that changes in blood flow are an accurate read-out of changes in ...
Attwell, D., Hall, C.N., Hamilton, N.B.
core +3 more sources
Case Reports in Oncology, 2013 Sunitinib malate (Sutent™; Pfizer Inc., New York, N.Y., USA) is a small molecule kinase inhibitor with activity against a number of tyrosine kinase receptors, including vascular endothelial growth factor receptors, stem-cell factor receptor, and platelet-
Tiziana Prochilo +6 more
doaj +1 more source
Mechanism of Hypercholesterolemia-Induced Atherosclerosis
Reviews in Cardiovascular Medicine, 2022 Hypercholesterolemia is involved in the development of atherosclerosis and is a risk factor for coronary artery disease, stroke, and peripheral vascular disease.
Kailash Prasad, Manish Mishra
doaj +1 more source
Platelets, 2022 Recent years have witnessed the introduction of ex vivo expanded dermal fibroblasts for several cell therapy and tissue-engineering applications, including the treatment of facial scars and burns, representing a promising cell type for regenerative ...
Beatriz Fernández Muñoz +9 more
doaj +1 more source
Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells [PDF]
, 2011 The molecular mechanism between atherosclerosis formation and periodontal pathogens is not clear although positive correlation between periodontal infections and cardiovascular diseases has been reported.
de Winther +23 more
core +2 more sources
Hypoxic Ventilatory Response in Platelet-Derived Growth Factor Receptor-β–Knockout Mice
Journal of Pharmacological Sciences, 2009 The present study investigated whether the platelet-derived growth factor receptor (PDGFR)-beta-mediated mechanisms are involved in the hypoxic ventilatory response through modulating the N-methyl-D-aspartate (NMDA) function. The ventilatory changes during hypoxic challenge (10% O(2), 30 min) were measured plethysmographically in mice selectively ...
Saori Tsunekawa +4 more
openaire +4 more sources
Austral Journal of Veterinary Sciences, 2017 Platelet-rich plasma is used as a treatment of arthropathies in horses. However, there is lack of in vitro information about the mechanism of action of this substance and its effects on healthy cartilage of these animals.
Jorge U. Carmona +2 more
doaj +1 more source
Direct interaction between Shc and the platelet-derived growth factor beta-receptor.
Journal of Biological Chemistry, 1994 The Src homology 2 (SH2) domain-containing Shc proteins p52shc and p46shc become phosphorylated upon activation of several tyrosine kinases and are implicated in mitogenic signal transduction. Ligand stimulation of the platelet-derived growth factor (PDGF) beta-receptor leads to autophosphorylation of tyrosine residues, which is known to mediate ...
K, Yokote +6 more
openaire +2 more sources
Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
, 2010 Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
core +1 more source