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Genetic Dissection of BDNF and TrkB Expression in Glial Cells

Biomolecules
The brain-derived neurotrophic factor (BDNF) and its high-affinity receptor tropomyosin-related kinase receptor B (TrkB) are widely expressed in the central nervous system. It is well documented that neurons express BDNF and full-length TrkB (TrkB.FL) as
Changran Niu +5 more
doaj +1 more source

Effects of tenuigenin on the expression of brain-derived neurotrophic factor and its receptor tyrosine protein kinase B in the hippocampus of Alzheimer's disease model rats

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Objective To investigate the effects of tenuigenin (TEN) on expression of brain-derived neurotrophic factor (BDNF), and its receptor tyrosine protein kinase B (TrkB) in the hippocampal CA1 region of Alzheimer's disease (AD) model rats.
Wei-rong CHEN, Yi-nan YAN, Hong-li CUI, Xin-yi LI +3 more
doaj

NTRK2 expression in gastrointestinal stromal tumors with a special emphasis on the clinicopathological and prognostic impacts

Scientific Reports
Gastrointestinal stromal tumors (GISTs) are typically characterized by activating mutations of the KIT proto-oncogene receptor tyrosine kinase (KIT) or platelet-derived growth factor receptor alpha (PDGFRA).
Keita Sasa +20 more
doaj +1 more source

Neurotrophic tyrosine kinase receptor 2 (NTRK2; TrkB) [PDF]

Science-Business eXchange, 2012
+6 more sources

Neurotrophic tyrosine kinase receptor 2 (NTRK2; TrkB) [PDF]

Science-Business eXchange, 2013
+6 more sources

Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk

Cell Reports
Summary: Cellular signaling involves a large repertoire of membrane receptors operating in overlapping spatiotemporal regimes and targeting many common intracellular effectors.
Cristina Lao-Peregrin +11 more
doaj +1 more source

Prevention of excitotoxicity-induced processing of BDNF receptor TrkB-FL leads to stroke neuroprotection. [PDF]