Results 1 to 10 of about 220,108 (349)

A role for myocilin in receptor-mediated endocytosis. [PDF]

PLoS One, 2013
Myocilin is a broadly expressed protein that when mutated uniquely causes glaucoma. While no function has been ascribed to explain focal disease, some properties of myocilin are known. Myocilin is a cytoplasmic protein that also localizes to vesicles specifically as part of a large membrane-associated complex with properties similar to the SNARE ...
McKay BS, Congrove NR, Johnson AA, Dismuke WM, Bowen TJ, Stamer WD.   +5 more
europepmc   +7 more sources

Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand [PDF]

, 1992
We have constructed an artificial ligand for the hepatocyte-specific asialoglycoprotein receptor for the purpose of generating a synthetic delivery system for DNA.
Ashwell G., Atherton E., Atherton E., Baenziger J. U., Christian Plank, Connolly D. T., Corley Cain C., Curiel D. T., DeWet J., Ellman G. L., Ernst Wagner, Gotten M., Gotten M., Gotten M., Huckett B., Karl Mechtler, Kempen H. J. M., Knowles B. B., Kurt Zatloukal, Lee Y. C., Matt Cotten, Orrantia E., Patek P.Q., Rosenkranz A. A., Seifter S., Severne Y., Spiess M., Tam J. P., Wagner E., Wagner E., Wagner E., Wagner E., Wharton S. A., Wu C., Wu G. Y., Zatloukal K., Zenke M.   +36 more
core   +2 more sources

Target shape dependence in a simple model of receptor-mediated endocytosis and phagocytosis. [PDF]

Proc Natl Acad Sci U S A, 2016
Phagocytosis and receptor-mediated endocytosis are vitally important particle uptake mechanisms in many cell types, ranging from single-cell organisms to immune cells.
Richards DM, Endres RG.
europepmc   +4 more sources

Receptor-Mediated Endocytosis in the Proximal Tubule. [PDF]

Annu Rev Physiol, 2017
Cells lining the proximal tubule (PT) of the kidney are highly specialized for apical endocytosis of filtered proteins and small bioactive molecules from the glomerular ultrafiltrate to maintain essentially protein-free urine. Compromise of this pathway results in low molecular weight (LMW) proteinuria that can progress to end-stage kidney disease ...
Eshbach ML, Weisz OA.
europepmc   +5 more sources

Receptor-mediated endocytosis [PDF]

Biochemical Journal, 1985
T E Wileman, Clifford V. Harding, Philip D. Stahl   +2 more
openaire   +4 more sources

ORAI channels are critical for receptor-mediated endocytosis of albumin. [PDF]

Nat Commun, 2017
AbstractImpaired albumin reabsorption by proximal tubular epithelial cells (PTECs) has been highlighted in diabetic nephropathy (DN), but little is known about the underlying molecular mechanisms. Here we find that ORAI1-3, are preferentially expressed in PTECs and downregulated in patients with DN.
Zeng B, Chen GL, Garcia-Vaz E, Bhandari S, Daskoulidou N, Berglund LM, Jiang H, Hallett T, Zhou LP, Huang L, Xu ZH, Nair V, Nelson RG, Ju W, Kretzler M, Atkin SL, Gomez MF, Xu SZ.   +17 more
europepmc   +6 more sources

Glycosylphosphatidylinositol-anchored receptor-mediated bacterial endocytosis [PDF]

FEMS Microbiology Letters, 2001
An increasing number of pathogens or their toxins appear to utilize glycosylphosphatidylinositol(GPI)-anchored receptors to trigger entry into immune and other host cells. Since these receptors have no transmembrane and intracellular moieties, how endocytosis is initiated is unclear.
Soman N. Abraham, Jeoung-Sook Shin
openaire   +4 more sources

Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype [PDF]

, 2012
Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs.
A Kihara, A Kissenpfennig, A Kumar, A Martino, A Olivera, A Weigert, AD Christensen, Burkhard Kleuser, C Ocana-Morgner, C Ruedl, CC Norbury, CL Bennett, CL Bennett, DH Kaplan, DH Kaplan, E Guaguere, ES Trombetta, EY Seo, F Sparber, G Gollmann, G Schuhmachers, H Hackstein, H Liu, Heinfried H. Radeke, HH Radeke, I Reines, J Chun, Jagadeesh Bayry, JH Hong, K Kabashima, K Sarkar, K Takabe, Katrin Schaper, L Japtok, L Rose, L Ruwisch, LS Bursch, Lukasz Japtok, M Hara-Chikuma, M Matloubian, M Schröder, M Schuppel, MB Lutz, MC Kerr, ML Allende, ML Allende, N Romani, P Mitra, P Monti, R van de Ven, RH Kim, RM Steinman, S Spiegel, S Sullivan, S Xu, Se Kyoo Jeong, SH Wood, SP Zahner, T Hla, T Kitajima, T Walzer, V Brinkmann, W Baumer, W Baumer, W Baumer, Wolfgang Bäumer, Y Maeda, Y Yanagawa, YY Lan   +68 more
core   +10 more sources

The mechanism of receptor‐mediated endocytosis [PDF]

European Journal of Biochemistry, 1991
Receptor-mediated endocytosis is a mechanism used by cells for the uptake of macromolecules from the extracellular fluid. It is a process found in all eukaryotic organisms in the plant and animal kingdoms. The early work of Roth and Porter (1964), which showed the uptake of yolk proteins into mosquito oocytes, first indicated that cells are capable of ...
Elizabeth Smythe, Graham Warren
openaire   +3 more sources

Mechanics of receptor-mediated endocytosis [PDF]

Proceedings of the National Academy of Sciences, 2005
Most viruses and bioparticles endocytosed by cells have characteristic sizes in the range of tens to hundreds of nanometers. The process of viruses entering and leaving animal cells is mediated by the binding interaction between ligand molecules on the viral capid and their receptor molecules on the cell membrane.
Wendong Shi, Huajian Gao, L. B. Freund
openaire   +3 more sources