Results 101 to 110 of about 734,847 (386)

NKG2D and its ligands: one for all, all for one [PDF]

open access: yes, 2018
The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina   +7 more
core   +2 more sources

Inhibition of dengue virus entry and multiplication into monocytes using RNA interference. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
BACKGROUND: Dengue infection ranks as one of the most significant viral diseases of the globe. Currently, there is no specific vaccine or antiviral therapy for prevention or treatment. Monocytes/macrophages are the principal target cells for dengue virus
Mohammed Abdelfatah Alhoot   +2 more
doaj   +1 more source

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL [PDF]

open access: gold, 2021
Artem A. Artykov   +5 more
openalex   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Galectin-3 Mediated Endocytosis of the Orphan G-Protein-Coupled Receptor GPRC5A

open access: yesCells
Galectins, a family of glycan-binding proteins, play crucial roles in various cellular functions, acting at both intracellular and extracellular levels.
Abdeldjalil Boucheham   +13 more
doaj   +1 more source

Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C disease

open access: yesJournal of Lipid Research, 2007
These studies explored the roles of receptor-mediated and bulk-phase endocytosis as well as macrophage infiltration in the accumulation of cholesterol in the mouse with Niemann-Pick type C (NPC) disease.
Benny Liu   +4 more
doaj   +1 more source

Duffy antigen receptor for chemokines mediates chemokine endocytosis through a macropinocytosis-like process in endothelial cells. [PDF]

open access: yesPLoS ONE, 2011
The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes and endothelial cells.
Yani Zhao   +6 more
doaj   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

open access: yesAdvanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich   +5 more
wiley   +1 more source

Understanding cellular internalization pathways of silicon nanowires [PDF]

open access: yes, 2017
BACKGROUND: Understanding how cells interact with nanomaterials is important for rational design of nanomaterials for nanomedicine and transforming them for clinical applications.
Huang, Yimin, McNear, Kelly, Yang, Chen
core   +1 more source

The nucleation of receptor-mediated endocytosis. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1996
A theory of the mechanical origins of receptor-mediated endocytosis shows that a spontaneous membrane complex formation can provide the stimulus for a local membrane motion toward the cytosol. This motion is identified with a nucleation stage of receptor-mediated endocytosis. When membrane complexes cluster, membrane deformation is predicted to be most
D A, Edwards   +4 more
openaire   +2 more sources

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