Results 211 to 220 of about 734,847 (386)

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

pH and the recycling of transferrin during receptor-mediated endocytosis.

Proceedings of the National Academy of Sciences of the United States of America, 1983
A. Dautry‐Varsat, A. Ciechanover, H. Lodish   +2 more
semanticscholar   +1 more source

PKC Is a Target to Modulate the Expression of Receptor Mediated Endocytosis (RME) Mice Macrophages BALB/c for Optimizing the Phagocytosis toward Candida albicans

, 2013
Adi Prayitno, Elyana Asnar, Okid Parama Astirin, Anief Nur Artanti, Meutia Srikandi Fitria, Eva Agustina Perwitasari, Suhartono Taat Putra   +6 more
openalex   +2 more sources

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

LDL receptor-mediated endocytosis of <i>Escherichia coli</i> α-hemolysin mediates renal epithelial toxicity. [PDF]

Proc Natl Acad Sci U S A
Kuhn HW, Smither MR, Jin RJ, Collins CA, Ma H, Sina J, Gaut JP, Diamond MS, Hunstad DA.   +8 more
europepmc   +1 more source

Receptor-Mediated Endocytosis of VEGF-A in Rat Liver Sinusoidal Endothelial Cells. [PDF]

Biomed Res Int, 2019
Mousavi SA, Skjeldal F, Fønhus MS, Haugen LH, Eskild W, Berg T, Bakke O.   +6 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals. [PDF]

Adv Sci (Weinh)
Chen SC, Zeng NJ, Liu GY, Wang HC, Lin TY, Tai YL, Chen CY, Fang Y, Chuang YC, Kao CL, Cheng H, Wu BH, Sun PC, Bayansan O, Chiu YT, Shih CH, Chung WH, Yang JB, Wang LH, Chiang PH, Chen CH, Wagner OI, Wang YC, Lin YC.   +23 more
europepmc   +1 more source

Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway

Pharmacological Reviews, 2002
Z. Qian, Hongyan Li, Hongzhe Sun, K. Ho
semanticscholar   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source