Results 21 to 30 of about 220,108 (349)
Effects of ligand distribution on receptor-diffusion-mediated cellular uptake of nanoparticles [PDF]
Royal Society Open Science, 2017 Biophysical-factor-dependent cellular uptake of nanoparticles (NPs) through receptor-diffusion-mediated endocytosis bears significance in pathology, cellular immunity and drug-delivery systems. Advanced nanotechnology of NP synthesis provides methods for
Long Li, Yudie Zhang, Jizeng Wang
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The Receptor-Mediated Endocytosis of Nonspherical Particles [PDF]
Biophysical Journal, 2008 Enveloped viruses and nanosized biomimetic particles for drug and gene delivery enter target cells mainly through receptor-mediated endocytosis. A few models have been presented to elucidate the mechanics of particle engulfment by the cell membrane, showing how size and surface chemico-physical properties favor or oppose internalization.
Paolo Decuzzi +3 more
openaire +3 more sources
Chemical Inhibitors of Dynamin Exert Differential Effects in VEGF Signaling
Cells, 2021 VEGFR2 is the main receptor and mediator of the vasculogenic and angiogenic activity of VEGF. Activated VEGFR2 internalizes through clathrin-mediated endocytosis and macropinocytosis.
Dimitris Basagiannis +5 more
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Effects of endocytosis on receptor-mediated signaling [PDF]
Current Opinion in Cell Biology, 2015 Cellular mechanisms of membrane traffic and signal transduction are deeply interconnected. The present review discusses how membrane trafficking in the endocytic pathway impacts receptor-mediated signaling. Examples of recent progress are highlighted, focusing on the endocytosis-signaling nexus in mammals.
Irannejad, Roshanak +3 more
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Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]
, 1993 The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna +5 more
core +3 more sources
Interaction among Saccharomyces cerevisiae pheromone receptors during endocytosis
Biology Open, 2014 This study investigates endocytosis of Saccharomyces cerevisiae α-factor receptor and the role that receptor oligomerization plays in this process. α-factor receptor contains signal sequences in the cytoplasmic C-terminal domain that are essential for ...
Chien-I Chang +2 more
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Receptor-Mediated Endocytosis in Plant Cells. [PDF]
The Plant Cell, 1989 We have employed fluorescein and 125l-labeled elicitors of the defense response in soybeans to monitor the cellular distribution and movement of elicitors following their addition to a soybean cell suspension culture. Our results indicate that the macromolecular elicitors first bind to the cell surface and then internalize in a temperature- and energy ...
Mark Alan Horn +2 more
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Visualization of Receptor-mediated Endocytosis in Yeast [PDF]
Molecular Biology of the Cell, 1999 We studied the ligand-induced endocytosis of the yeast α-factor receptor Ste2p by immuno-electron microscopy. We observed and quantitated time-dependent loss of Ste2p from the plasma membrane of cells exposed to α-factor. This ligand-induced internalization of Ste2p was blocked in the well-characterized endocytosis-deficient mutant sac6Δ.
Marino Zerial +4 more
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Dynamin-dependent NMDAR endocytosis during LTD and its dependence on synaptic state
BMC Neuroscience, 2005 Background The N-methyl-D-aspartate (NMDA)-type glutamate receptor expressed at excitatory glutamatergic synapses is required for learning and memory and is critical for normal brain function.
Hanson Jesse E +3 more
doaj +1 more source
Transferrin-polycation conjugates as carriers for DNA uptake into cells. [PDF]
, 1990 We have developed a high-efficiency nucleic acid delivery system that uses receptor-mediated endocytosis to carry DNA macromolecules into cells. We accomplished this by conjugating the iron-transport protein transferrin to polycations that bind nucleic ...
Beug, Hartmut +4 more
core +1 more source