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Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li+8 more
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Mdm2-Mediated Ubiquitination Plays a Pivotal Role in Differentiating the Endocytic Roles of GRK2 and Arrestin3. [PDF]
Wang S+5 more
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Cholesterol-rich lipid rafts mediate endocytosis as a common pathway for respiratory syncytial virus entry into different host cells. [PDF]
Zhou A+9 more
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Innately Fluorescent Tetravalent Cytotoxic Conjugate TetraF<sub>HER2</sub>-vcMMAE Engages Aggregation-Dependent Endocytosis of HER2 for Enhanced Intracellular Drug Delivery. [PDF]
Porębska N+6 more
europepmc +1 more source
Cell-penetrating peptides as facilitators of cargo-specific nanocarrier-based drug delivery.
Jankowski AM, Ensign MA, Maisel K.
europepmc +1 more source
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Receptor-mediated endocytosis and cytoskeleton
Biochemistry (Moscow), 2014Receptor-mediated endocytosis is the most specific pathway for macromolecules and macromolecular complexes generally designated as ligands to enter cells. Upon binding to their transmembrane receptors, the ligands enter endocytic vesicles that fuse with each other giving rise to the so-called early endosomes.
Elena S. Kornilova, Elena S. Kornilova
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