Results 181 to 190 of about 3,521,155 (317)

Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo

, 1997
Patrick C.N. Rensen, Nicole Herijgers, M.H. Netscher, Stefan C. J. Meskers, Miranda Van Eck, T J van Berkel   +5 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Cryo-EM of autoantibody-bound NMDA receptors reveals antigenic hotspots in an active immunization model of anti-NMDAR encephalitis. [PDF]

Sci Adv
Kim J, Jalali-Yazdi F, Jones BE, Westbrook GL, Gouaux E.   +4 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

From Single Ligand-Receptor Bond Strength to Collective Avidity: Mechanics-Guided Superselective Nanoparticle Adhesion to Biological Membranes. [PDF]

Langmuir
Hamzeh M, Mirahsani S, Ahmadpoor F, Farokhirad S.   +3 more
europepmc   +1 more source

Mutation of a ligand binding domain of beta 3 integrin. Integral role of oxygenated residues in alpha IIb beta 3 (GPIIb-IIIa) receptor function.

, 1994
Mary Lynn Bajt, Joseph C. Loftus
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Potential treatment of COVID-19 by inhibitors of human dihydroorotate dehydrogenase

Protein & Cell, 2020
Yechun Xu, Hualiang Jiang
doaj   +1 more source

Letter to the Editor: Dopamine D2S/D2L Receptor Regulation of Alcohol-Induced Reward and Signalling. [PDF]

Addict Biol
Tariq M, Ahmad M, Hayat MZ, Khalid MH.
europepmc   +1 more source

Midline crossing by gustatory receptor neuron axons is regulated byfruitless, doublesexand the Roundabout receptors

, 2009
David J. Mellert, Jon-Michael Knapp, Devanand S. Manoli, Geoffrey W Meissner, Bruce S. Baker   +4 more
openalex   +2 more sources