Results 181 to 190 of about 3,511,004 (317)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Receptor dimerization enables ligand discrimination through tunable response heterogeneity. [PDF]

PLoS Comput Biol
Biran A, Antebi YE.
europepmc   +1 more source

Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1·GTP pathway

, 2009
Shang‐Yi Tsai, Teruo Hayashi, Brandon K. Harvey, Yun Wang, Wells W. Wu, Rong‐Fong Shen, Yongqing Zhang, Kevin G. Becker, Barry J. Hoffer, Tsung‐Ping Su   +9 more
openalex   +1 more source

Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference [PDF]

, 2019
Min‐Ho Nam, Kyung‐Seok Han, Jaekwang Lee, Woojin Won, Wuhyun Koh, Jin Young Bae, Junsung Woo, Jayoung Kim, Elliot Kwong, Tae-Yong Choi, Heejung Chun, Seung Eun Lee, Gi-Chang Kim, Ki Duk Park, Se‐Young Choi, Yong Chul Bae, C. Justin Lee   +16 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Comparative dementia risk with GLP1 receptor agonists, SGLT2 inhibitors, or DPP4 inhibitors: a population-based cohort study. [PDF]

Alzheimers Res Ther
Wu CY, Alkabbani W, Shah BR, Kapral MK, Edwards JD, Maxwell CJ, Swardfager W.   +6 more
europepmc   +1 more source

Quantification of expression of netrins, slits and their receptors in human prostate tumors

, 2002
Alain Latil, Laurent Chêne, Béatrix Cochant‐Priollet, Philippe Mangin, Georges Fournier, Philippe Berthon, Olivier Cussenot   +6 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Potential treatment of COVID-19 by inhibitors of human dihydroorotate dehydrogenase

Protein & Cell, 2020
Yechun Xu, Hualiang Jiang
doaj   +1 more source