Results 191 to 200 of about 7,559,498 (434)

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Efficiency of initiating cell adhesion in hydrodynamic flow

open access: yes, 2006
We theoretically investigate the efficiency of initial binding between a receptor-coated sphere and a ligand-coated wall in linear shear flow. The mean first passage time for binding decreases monotonically with increasing shear rate.
A. Pierres   +5 more
core   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Structural characterization of FZD7, the importance of water network and cholesterol for class F GPCRS [PDF]

open access: yesBIO Web of Conferences
Bous Julien   +7 more
doaj   +1 more source

Nothing Besides Remains: Preserving the Scientific and Cultural Value of Paleontological Resources in the United States [PDF]

open access: yes, 2005
Receptor occupancy assessed by Positron Emission Tomography (PET) can provide important translational information to help bridge information from one drug to another or from animal to man.
Chew, Alexa Z.
core   +1 more source

Evidence of the Atrial Location of Receptors Influencing Urine Flow

open access: bronze, 1956
James P. Henry   +2 more
openalex   +1 more source

The capsaicin receptor: a heat-activated ion channel in the pain pathway

open access: yesNature, 1997
M. Caterina   +5 more
semanticscholar   +1 more source

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