Results 291 to 300 of about 7,559,498 (434)

Pleiotropic neurotransmitters: neurotransmitter-receptor crosstalk regulates excitation-inhibition balance in social brain functions and pathologies. [PDF]

Front Neurosci
Chai A.
europepmc   +1 more source

Studies in immunochemistry. 18. The isolation and properties of a sialomucopolysaccharide possessing blood-group Lea specificity and virus-receptor activity [PDF]

, 1961
Árpád Pusztai, W. T. J. Morgan
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies. [PDF]

Mil Med Res
Liang TZ, Jin ZY, Lin YJ, Chen ZY, Li Y, Xu JK, Yang F, Qin L.   +7 more
europepmc   +1 more source

Early receptor potential in the human eye. [PDF]

, 1967
Nicholas R. Galloway
openalex   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

A "Dock-Work" Orange: A Dual-Receptor Biochemical Theory on the Deterrence Induced by Citrusy Aroma on Elephant Traffic Central to a Conservation Effort. [PDF]

Bioinform Biol Insights
Gunawardana D.
europepmc   +1 more source

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

Nature, 1984
A. Dalgleish, P. Beverley, P. Clapham, D. Crawford, M. Greaves, R. Weiss   +5 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Advances in PET Imaging of α7 Nicotinic Receptors: From Radioligand Development to CNS Applications. [PDF]

Basic Clin Pharmacol Toxicol
Magnussen JH.
europepmc   +1 more source