Results 321 to 330 of about 6,048,033 (361)

Receptors

1992
Publisher Summary This chapter presents the pharmacodynamics of drug-receptor interactions. Because of the low concentration of drugs and receptors in the bloodstream and other biological fluids, the law of the mass action alone cannot account for the ability of small doses of structurally specific drugs to elicit a total response.
Richard B. Silverman, Mark W. Holladay
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Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology

Brain Research Reviews, 2008
Future therapies for diseases associated with altered dopaminergic signaling, including Parkinson's disease, schizophrenia and drug addiction or drug dependence may substantially build on the existence of intramembrane receptor-receptor interactions within dopamine receptor containing receptor mosaics (RM; dimeric or high-order receptor oligomers ...
Fuxe K, Marcellino D, Rivera A, Diaz Cabiale Z, Filip M, Gago B, Roberts DC, Langel U, Genedani S, FERRARO, Luca Nicola, de la Calle A, Narvaez J, TANGANELLI, Sergio, Woods A, Agnati L.F.   +14 more
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Receptor Regulation and Receptor-Receptor Communication

1987
As recently as five years ago, what one might term the “grind and bind era” of receptor studies was still in full bloom; and a large number of studies were focussed on determining receptor affinities and numbers under a variety of physiologic situations.
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Bradykinin receptors and receptor ligands (with special emphasis on vascular receptors)

Regulatory Peptides, 1996
Bradykinin and receptor ...
REGOLI, Domenico, CALO', Girolamo, RIZZI, Anna, BOGONI G, GOBEIL F, CAMPOBASSO C, MOLLICA, Gioacchino, BEANI, Lorenzo   +7 more
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Enigmatic receptors

Pharmaceutica Acta Helvetiae, 2000
The identification of new binding sites raises the problem of defining their role, if any. At times they are shown to be pharmacological receptors, in a strict sense, as they fulfill certain requirements, and a precise physiological role and function, and an endogenous ligand (neurotransmitter) are discovered.
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Androgen Receptor and Estrogen Receptors

2002
The androgen receptor (AR) and the estrogen receptors (ER) are members of the nuclear receptor (NR) family. These NRs are distinguished from the other transcription factors by their ability to control gene expression upon ligand binding (steroids, retinoids, thyroid hormone, vitamin D, fatty acids, and other small hydrophobic molecules). Their combined
H. M. Oosterkamp, R. Bernards
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Adenosine receptors: Intermembrane receptor–receptor interactions in the brain

Synergy, 2014
Summary In the vertebrate central nervous system (CNS) the modulation of synaptic transmission by metabotropic or ionotropic receptors is an important source of control and dynamical adjustment in synaptic activity and can contribute to synergistic or antagonistic effects.
Karen Nieber, Sebastian Michael
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The thyrotropin receptor as a model to illustrate receptor and receptor antibody diseases

Baillière's Clinical Endocrinology and Metabolism, 1995
The thyrotropin receptor (TSHR) has been used as an example to illustrate how disease may be the consequence of: 1. Modifications or inappropriate production of the natural ligand. 2. Production of abnormal agonists or antagonists such as autoantibodies. 3.
Ludgate, Marian, Vassart, Gilbert
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Gonadotropin Receptors

2016
The two gonadotrophin receptors (GnRs), luteinizing hormone receptor (LHCGR) and follicle-stimulating receptor (FSHR), belong to the glycoprotein hormone receptor subgroup of type A G protein-coupled receptors (GPCRs). LHCGR binds specifically the two structurally similar gonadotrophins, luteinizing hormone (LH) and human chorionic gonadotrophin (hCG),
CASARINI, Livio, Huhtaniemi, Ilpo, SIMONI, Manuela, Rivero Müller, Adolfo   +3 more
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Melatonin Receptor Signaling: Impact of Receptor Oligomerization on Receptor Function

2018
The melatonin receptor subfamily is composed of three members, MT1 and MT2, which are binding to melatonin, and GPR50, which shows high sequence homology to MT1 and MT2 but does not bind to melatonin or any other known ligand. An interesting feature of these receptors is their capacity to form homo- and heteromers between each other and also with other
Ralf Jockers, Ralf Jockers, Ralf Jockers, Erika Cecon, Atsuro Oishi   +4 more
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