Results 361 to 370 of about 7,559,498 (434)
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To be or not to be (a receptor)
Steroids, 2007In addition to cellular responses that are elicited by steroids involving the modulation of transcription in the nucleus, it is now generally accepted that additional phenomena occur that do not depend on the genome. However, there is a puzzling variety of candidate receptors described in the literature.
Ralf Lösel, Martin Wehling, A. Schultz
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Science, 1987
The primary structure of T cell receptor proteins and genes is well understood. Immunologists are now trying to understand the properties of these interesting molecules. Evidence suggests that T cell αβ receptors recognize a complex of an antigen-derived peptide bound to one of the cell-surface products of the major histocompatibility complex (MHC ...
John W. Kappler, Philippa Marrack
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The primary structure of T cell receptor proteins and genes is well understood. Immunologists are now trying to understand the properties of these interesting molecules. Evidence suggests that T cell αβ receptors recognize a complex of an antigen-derived peptide bound to one of the cell-surface products of the major histocompatibility complex (MHC ...
John W. Kappler, Philippa Marrack
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Interleukin-10 and the interleukin-10 receptor.
Annual Review of Immunology, 2001Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell types. The principal routine function
K. Moore +3 more
semanticscholar +1 more source
Cellular and Molecular Life Sciences (CMLS), 2004
Olfaction is an ancient sensory system allowing an organism to detect chemicals in its environment. The first step in odor transduction is mediated by binding odorants to olfactory receptors (ORs) which belong to the heptahelical G-protein-coupled receptor (GPCR) superfamily. Mammalian ORs are disposed in clusters on virtually all chromosomes. They are
Giorgi, Dominique +2 more
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Olfaction is an ancient sensory system allowing an organism to detect chemicals in its environment. The first step in odor transduction is mediated by binding odorants to olfactory receptors (ORs) which belong to the heptahelical G-protein-coupled receptor (GPCR) superfamily. Mammalian ORs are disposed in clusters on virtually all chromosomes. They are
Giorgi, Dominique +2 more
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Crystal Structure of Rhodopsin: A G‐Protein‐Coupled Receptor
ChemBioChem, 2002G-protein-coupled receptors (GPCRs) provide a molecular link between extracellular signals and intracellular processes. In the visual system, GPCRs such as rhodopsin and cone visual pigments absorb photons and initiate G-protein signal transduction ...
R. Stenkamp, D. Teller, K. Palczewski
semanticscholar +1 more source
Cellular and Molecular Life Sciences, 2008
Glucagon is a pancreatic peptide hormone that, as a counterregulatory hormone for insulin, stimulates glucose release by the liver and maintains glucose homeostasis. First described as a glucagon binding entity functionally linked to adenylyl cyclase, the glucagon receptor is a member of the family B receptors within the G protein coupled superfamily ...
Authier, François, Desbuquois, Bernard
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Glucagon is a pancreatic peptide hormone that, as a counterregulatory hormone for insulin, stimulates glucose release by the liver and maintains glucose homeostasis. First described as a glucagon binding entity functionally linked to adenylyl cyclase, the glucagon receptor is a member of the family B receptors within the G protein coupled superfamily ...
Authier, François, Desbuquois, Bernard
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G proteins: transducers of receptor-generated signals.
Annual Review of Biochemistry, 1987PERSPECTIVES AND SUMMARy ......... .. ........ . ...... 615 HISTORy ....... ...... . . . . . ...... . . .. .... . . . .. . 616 INDIVIDUAL G PROTEINS: FUNCTIONS AND MOLECULAR ENTITIES 617 Criter ia for In volvemen t o f a G Pr otein ..... .........
A. Gilman
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Isolation and structure of a brain constituent that binds to the cannabinoid receptor.
Science, 1992Arachidonylethanolamide, an arachidonic acid derivative in porcine brain, was identified in a screen for endogenous ligands for the cannabinoid receptor.
W. Devane +9 more
semanticscholar +1 more source
Science Signaling, 2008
Toll-like receptors recognize molecules associated with pathogens and initiate inflammatory responses. For example, Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA), an intermediate viral replication. The TLR3 ectodomain binds as a dimer to dsRNA, but the molecular basis for signaling remains unclear.
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Toll-like receptors recognize molecules associated with pathogens and initiate inflammatory responses. For example, Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA), an intermediate viral replication. The TLR3 ectodomain binds as a dimer to dsRNA, but the molecular basis for signaling remains unclear.
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