Results 51 to 60 of about 4,238,851 (307)

Pathogenicity, transmissibility, and receptor binding of a human-isolated influenza A (H10N5) virus

mBio
Recently, human infections with H10 influenza viruses, including H10N8 and H10N3, have been reported. In January 2024, a case of H10N5 and H3N2 co-infection was reported in Zhejiang Province, China, which is the first human infection with H10N5 avian ...
Mengchan Hao, Jiaying Wu, Lina Ji, Yubo Zhao, Shunyuan Zhang, Yiwei Guan, Liangyu Li, Wenxue Yang, Yuan Zhang, Jianjun Chen   +9 more
doaj   +1 more source

A Novel Reassortant Avian H7N6 Influenza Virus Is Transmissible in Guinea Pigs via Respiratory Droplets

Frontiers in Microbiology, 2019
Since 2013, H7N9 and H5N6 avian influenza viruses (AIVs) have caused sporadic human infections and deaths and continued to circulate in the poultry industry.
Zongzheng Zhao, Zongzheng Zhao, Lina Liu, Zhendong Guo, Chunmao Zhang, Zhongyi Wang, Guoyuan Wen, Wenting Zhang, Yu Shang, Tengfei Zhang, Zuwu Jiao, Ligong Chen, Cheng Zhang, Huan Cui, Meilin Jin, Chengyu Wang, Qingping Luo, Huabin Shao   +17 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Relevance of potential endocytosis motifs in Cedar virus glycoprotein G for its biological activity

Journal of Virology
The glycoprotein (G) and fusion protein (F) of henipaviruses play crucial roles in receptor binding and entry into host cells, also enabling virus spread from cell to cell without the release of infectious particles.
Céline Burrer, Inga Hund, Carolin Rüdiger, Sven Reiche, Martin H. Groschup, Birke A. Tews, Dmitry S. Ushakov, Kerstin Fischer, Sandra Diederich   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

3D model of amphioxus steroid receptor complexed with estradiol [PDF]

, 2009
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
Michael E. Baker, David J. Chang
core  

An Olfactory Receptor Pseudogene whose Function emerged in Humans [PDF]

, 2007
Human olfactory receptor, hOR17-210, is identified as a pseudogene in the human genome. Experimental data has shown however, that the gene product of cloned hOR17-210 cDNA was able to bind an odorant-binding protein and is narrowly tuned for excitation ...
Gautam Bahl, Valery Matarazzo, Chiquito J. Crasto, Peter Lai, Olivier Clot-Faybesse, Catherine Ronin, Maryse Gremigni, Valery Matarazzo, Chiquito Crasto   +8 more
core   +1 more source

Conserved tripartite tail proteins mediate virophage-host interactions through Synechococcus lipopolysaccharide binding

Journal of Virology
Virophages are small double-stranded DNA viruses that parasitize giant viruses and play crucial roles in microbial ecosystem dynamics. In this study, we investigate three evolutionarily conserved tail proteins in Dishui Lake Virophage 2 (DSLV2) that ...
Ting Chu, Qinran Wang, Chen Hu, Zexian Zhou, Bo Li, Yesheng Yan, Xiang Li, Aohan Wang, Qianglin Fang, Shuling Yan, Lanming Chen, Yongxin Yu, Yongjie Wang   +12 more
doaj   +1 more source

The SARS-CoV-2 Spike Glycoprotein as a Drug and Vaccine Target: Structural Insights into Its Complexes with ACE2 and Antibodies

Cells, 2020
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of the Coronavirus disease (COVID-19) pandemic, has so far resulted in more than 1.1 M deaths and 40 M cases worldwide with no confirmed remedy yet available.
Anastassios C. Papageorgiou, Imran Mohsin   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source