Results 91 to 100 of about 38,514 (297)

Advanced glucose control strategies leveraging Raman spectroscopy for optimized mammalian cell culture manufacturing

Biotechnology Progress, EarlyView.
Abstract Maintaining consistent quality in the manufacturing of biotherapeutic proteins in mammalian cell culture is challenging, with unplanned deviations causing inconsistencies and potential batch failure. Current methods for monitoring and controlling critical process parameters (CPPs) rely on slow, labor‐intensive offline analyses.
Matthew Banner, Daniel Ray, Irfan Ahanger, Fabio Zurlo, Noah Hitchcock, Rajesh Mistry, Kasia Kozakowska‐McDonnell, Matthew Cheeks, Richard Turner, Jonathan Welsh, Suzanne S. Farid, Michael Thomas, Stephen Goldrick   +12 more
wiley   +1 more source

Levels of Soluble Receptor for Advanced Glycation End Products in Bronchoalveolar Lavage Fluid in Patients with Various Inflammatory Lung Diseases [PDF]

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2016
Tetsuro Kamo, Sadatomo Tasaka, Yuriko Tokuda, Shoji Suzuki, Takanori Asakura, Kazuma Yagi, Ho Namkoong, Makoto Ishii, Naoki Hasegawa, Tomoko Betsuyaku   +9 more
doaj   +1 more source

The AGE–RAGE–oxidative stress axis: A paradigm shift in understanding diabetic retinopathy

Indian Journal of Ophthalmology
Diabetic retinopathy (DR) represents a vision-threatening complication of diabetes, characterized by progressive damage to the retinal neurovascular network in both type 1 and type 2 diabetes.
Riya Srivastava, Deepak Mishra, Dipti Singh, M Yashwant Reddy, Samvidha Parihar, Kamlesh Palandurkar   +5 more
doaj   +1 more source

Explore the mechanism of puerarin to improve diabetic peripheral neuropathy in rats based on AGEs/RAGE signaling pathway [PDF]

Yixue xinzhi zazhi
Objective To explore the ameliorative effect of puerarin on diabetic peripheral neuropathy (DPN) in rats and its possible mechanism.Methods A total of 50 SD rats were randomly divided into control group, model group (DPN model was constructed), low-dose ...
HAO Lu, SHI Mingyang, CHEN Yan, YANG Shan   +3 more
doaj   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Skin autofluorescence in diabetes mellitus [PDF]

, 2008
AGEs ofwel advanced glycation endproducts zijn onomkeerbaar versuikerde stoffen, die voornamelijk aan eiwitten zijn gekoppeld, en die bij ieder mens stapelen. Bij iemand met diabetes mellitus gaat dit proces echter versneld.
Lutgers, Helen Lucia, Lutgers, H.L.,, Lutgers, H.L.   +2 more
core  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis [PDF]

, 2016
The receptor for advanced glycation end products (RAGE) is a novel protein increasingly studied in the pathogenesis of type 1 diabetes (T1D). RAGE is expressed by several immune cell types, including T cells, antigen-presenting cells, endothelial cells ...
Leung, Sherman S., Forbes, Josephine M., Borg, Danielle J.   +2 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Clinical Factors and Biomarkers Associated with Depressive Disorders in Older Patients Affected by Chronic Kidney Disease (CKD): Does the Advanced Glycation End Products (AGEs)/RAGE (Receptor for AGEs) System Play Any Role?

Geriatrics
Depressive disorders are highly prevalent among subjects suffering from chronic kidney disease (CKD). The aim of the present study is to evaluate clinical and biochemical factors associated with depressive disorders in a sample of older CKD patients ...
Massimiliano Buoli, Elena Dozio, Lara Caldiroli, Silvia Armelloni, Elena Vianello, Massimiliano Corsi Romanelli, Giuseppe Castellano, Simone Vettoretti   +7 more
doaj   +1 more source