Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs [PDF]
Cells, 2022 Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse group of compounds formed either exogeneously or endogeneously on the course of various pathways in the human body.
Aleksandra Twarda-Clapa +3 more
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Advanced Glycation End-Products (AGEs) and Their Soluble Receptor (sRAGE) in Women Suffering from Systemic Lupus Erythematosus (SLE) [PDF]
Cells, 2021 Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak +5 more
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Pharmacologic approaches against Advanced Glycation End Products (AGEs) in diabetic cardiovascular disease [PDF]
Research in Cardiovascular Medicine, 2015 Context: Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Antonio Nenna +6 more
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Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation [PDF]
Free Radical Research, 2013 Advanced lipoxidation end products (ALEs) and advanced glycation end products (AGEs) have a pathogenetic role in the development and progression of different oxidative-based diseases including diabetes, atherosclerosis, and neurological disorders.
Neven Zarkovic, Giancarlo Aldini
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Oxidative Stress, Advanced Glycation End Products (AGEs), and Neurodegeneration in Alzheimer’s Disease: A Metabolic Perspective [PDF]
AntioxidantsNeurodegenerative diseases such as Alzheimer’s disease (AD) are closely linked to oxidative stress and advanced glycation end products (AGEs), two interrelated processes that exacerbate neuronal damage through mitochondrial dysfunction, protein ...
Virginia Boccardi +2 more
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Lens Autofluorescence Based Advanced Glycation End Products (AGEs) Measurement to Assess Risk of Osteopenia Among Individuals Under the Age of 50 [PDF]
Medical Devices: Evidence and Research, 2022 Shaoyun Li,1,* Yuefei Li,1,* Xiyan Xu,1 Jian Shao,2 Ruifeng Xie,3 Sheng Liu,1 Li Peng,1 Jin Wang,1 Kaixin Zhou,3 Huyi Feng1 1The Fifth People’s Hospital of Chongqing, Chongqing, People’s Republic of China; 2Guangzhou Laboratory, Guangzhou, People’
Li S +9 more
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Advanced glycation end products regulate the receptor of AGEs epigenetically
Frontiers in Cell and Developmental Biology, 2023 Advanced glycation end-products (AGEs) can boost their receptor of AGE (RAGE) expression through the downstream signaling pathway to facilitate AGE–RAGE interaction. In this regulation process, the primary signaling pathways are NF-κB and STAT3. However,
Xiaoqing Wu +4 more
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Contribution of Glycation and Oxidative Stress to Thyroid Gland Pathology—A Pilot Study
Biomolecules, 2021 The patho-mechanism of changes in the thyroid gland, including carcinogenesis, is a complex process, which involves oxidative stress. The goal of our investigation was to verify the extent of stress in the thyroid gland related to glycation.
Aleksandra Kuzan +8 more
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Advanced Glycation End Products and Psoriasis
Vaccines, 2023 Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli +2 more
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Synthesis and evaluation of naphthoic acid derivatives as fluorescent probes to screen advanced glycation end-products breakers [PDF]
, 2012 Advanced glycation end-products, namely AGEs, are involved in the pathogenesis of numerous diseases. If AGEs inhibitors are well-known, only few products are described as compounds able to destroy those deleterious products.
D. Seraphin +6 more
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