Results 11 to 20 of about 24,686 (257)

Advanced glycation end products [PDF]

Dermato-Endocrinology, 2012
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
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Advanced Glycation End Products and Psoriasis

Vaccines, 2023
Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni   +2 more
doaj   +1 more source

Advanced Glycation End Product Recognition by the Receptor for AGEs [PDF]

Structure, 2011
Nonenzymatic protein glycation results in the formation of advanced glycation end products (AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's disease, and cancer. AGEs mediate their effects primarily through a receptor-dependent pathway in which AGEs bind to a specific cell surface associated receptor, the ...
Xue, Jing, Rai, Vivek, Singer, David, Chabierski, Stefan, Xie, Jingjing, Reverdatto, Sergey, Burz, David S., Schmidt, Ann Marie, Hoffmann, Ralf, Shekhtman, Alexander   +9 more
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Advanced Glycation End Products (AGEs) Webinar Meeting Report. [PDF]

J Diabetes Sci Technol
The advanced glycation end products (AGEs) Webinar was co-hosted by Diabetes Technology Society and Kitalys Institute on August 8, 2024, with the goal of reviewing progress made in the measurement and use of AGEs in clinical practice. Meeting topics included (1) AGEs as predictors of diabetic nephropathy (DKD), (2) hemoglobin glycation index (HGI) and ...
Ho CN, Ayers AT, Beisswenger P, Chalew S, Schmidt AM, Pandey A, Kapahi P, Fleming A, Klonoff DC.   +8 more
europepmc   +3 more sources

Do advanced glycation end products contribute to food allergy?

Frontiers in Allergy, 2023
Sugars can bind non-enzymatically to proteins, nucleic acids or lipids and form compounds called Advanced Glycation End Products (AGEs). Although AGEs can form in vivo, factors in the Western diet such as high amounts of added sugars, processing methods ...
P. K. Smith, C. Venter, L. O’Mahony, R. Berni Canani, O. J. L. Lesslar   +4 more
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Serum Levels of Antibodies to Advanced Glycation End Products in Patients with Type 2 Diabetes Mellitus and Hypertension [PDF]

Folia Medica, 2020
Background and Aims: Proteins containing advanced glycation end products are highly immunogenic and anti-advanced glycation end products antibodies (anti-AGEs antibodies) are found in the sera of diabetics.Materials and methods: Enzyme-linked ...
Asparuh Nikolov, Alexander Blazhev, Maria Tzekova, Konstantin Kostov, Nikola Popovski   +4 more
doaj   +3 more sources

Aging ovary and the role for advanced glycation end products

Menopause, 2017
Abstract Objective: The hypothalamic gonadotropin-releasing hormone pulse generator, the pituitary gonadotropes, the ovaries, and the uterus play a crucial role in female fertility. A decline in reproductive performance represents a complex interplay of actions at all levels of the hypothalamic-pituitary-ovarian axis.
Pertynska-Marczewska, Magdalena, Diamanti-Kandarakis, Evanthia   +1 more
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Association of advanced glycation end products in Dupuytren disease

Journal of Orthopaedic Surgery and Research, 2018
Background Advanced glycation end products are associated with aging, hyperglycemia, and oxidative stress. Accumulation of advanced glycation end products can cause various pathological conditions; however, the association of Dupuytren’s disease with ...
Fumiaki Takase, Yutaka Mifune, Atsuyuki Inui, Yasuhiro Ueda, Takeshi Kataoka, Takeshi Kokubu, Ryosuke Kuroda   +6 more
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The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer's Disease. [PDF]

PLoS ONE, 2015
Amyloid precursor protein (APP) has been modified by β and γ-secretase that cause amyloid deposits (plaques) in neuronal cells. Glyceraldhyde-derived AGEs has been identified as a major source of neurotoxicity in Alzheimer's disease (AD).
Shun-Yao Ko, Hshin-An Ko, Kuo-Hsiung Chu, Tzong-Ming Shieh, Tzong-Cherng Chi, Hong-I Chen, Weng-Cheng Chang, Shu-Shing Chang   +7 more
doaj   +1 more source

Protein glycoxidation in neuropsychiatric disorders—from basic research to clinical practice

Redox Biology
This review integrates current findings on protein glycation, glycoxidation, and carbonyl stress in selected neurodegenerative and neuropsychiatric disorders, with a particular focus on mechanistic pathways relevant to Alzheimer's disease (AD), Parkinson'
Wiktor Orlof, Mateusz Maciejczyk
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