Results 11 to 20 of about 42,960 (301)

Advanced Glycation End-Products in Skeletal Muscle Aging [PDF]

Bioengineering, 2021
Advanced age causes skeletal muscle to undergo deleterious changes including muscle atrophy, fast-to-slow muscle fiber transition, and an increase in collagenous material that culminates in the age-dependent muscle wasting disease known as sarcopenia. Advanced glycation end-products (AGEs) non-enzymatically accumulate on the muscular collagens in old ...
Lucas C. Olson, James T. Redden, Zvi Schwartz, David J. Cohen, Michael J. McClure   +4 more
openaire   +3 more sources

A Role for Advanced Glycation End Products in Molecular Ageing

International Journal of Molecular Sciences, 2023
Ageing is a composite process that involves numerous changes at the cellular, tissue, organ and whole-body levels. These changes result in decreased functioning of the organism and the development of certain conditions, which ultimately lead to an increased risk of death.
Katarzyna Zgutka, Marta Tkacz, Patrycja Tomasiak, Maciej Tarnowski   +3 more
openaire   +2 more sources

Dietary Advanced Glycation End Products and Aging [PDF]

Nutrients, 2010
Advanced glycation end products (AGEs) are a heterogeneous, complex group of compounds that are formed when reducing sugar reacts in a non-enzymatic way with amino acids in proteins and other macromolecules. This occurs both exogenously (in food) and endogenously (in humans) with greater concentrations found in older adults.
Luevano-Contreras, Claudia, Chapman-Novakofski, Karen   +1 more
openaire   +2 more sources

Advanced glycation end products [PDF]

Dermato-Endocrinology, 2012
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire   +2 more sources

Advanced Glycation End Product Recognition by the Receptor for AGEs [PDF]

Structure, 2011
Nonenzymatic protein glycation results in the formation of advanced glycation end products (AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's disease, and cancer. AGEs mediate their effects primarily through a receptor-dependent pathway in which AGEs bind to a specific cell surface associated receptor, the ...
Xue, Jing, Rai, Vivek, Singer, David, Chabierski, Stefan, Xie, Jingjing, Reverdatto, Sergey, Burz, David S., Schmidt, Ann Marie, Hoffmann, Ralf, Shekhtman, Alexander   +9 more
openaire   +2 more sources

Advanced Glycation End Products (AGEs) Webinar Meeting Report. [PDF]

J Diabetes Sci Technol
The advanced glycation end products (AGEs) Webinar was co-hosted by Diabetes Technology Society and Kitalys Institute on August 8, 2024, with the goal of reviewing progress made in the measurement and use of AGEs in clinical practice. Meeting topics included (1) AGEs as predictors of diabetic nephropathy (DKD), (2) hemoglobin glycation index (HGI) and
Ho CN, Ayers AT, Beisswenger P, Chalew S, Schmidt AM, Pandey A, Kapahi P, Fleming A, Klonoff DC.   +8 more
europepmc   +3 more sources

Do advanced glycation end products contribute to food allergy?

Frontiers in Allergy, 2023
Sugars can bind non-enzymatically to proteins, nucleic acids or lipids and form compounds called Advanced Glycation End Products (AGEs). Although AGEs can form in vivo, factors in the Western diet such as high amounts of added sugars, processing methods ...
P. K. Smith, C. Venter, L. O’Mahony, R. Berni Canani, O. J. L. Lesslar   +4 more
doaj   +1 more source

The critical role of methylglyoxal and glyoxalase 1 in diabetic nephropathy [PDF]

, 2013
The discovery of increased formation of methylglyoxal (MG) by cell metabolism in high glucose concentration in vitro suggested possible relevance to diabetes and diabetes complications (1,2).
Rabbani, Naila, Thornalley, Paul J.
core   +1 more source

Advanced Glycation end products (AGEs) in food: focusing on Mediterranean pasta [PDF]

, 2015
5Advanced glycation end products, also known as glycotoxins, are a diverse group of highly oxidant compounds with pathogenic significance in aged-chronic disease, including diabetes, cardiovascular disease and neurodegenerative disease. They are produced
Abate, Giulia, Delbarba, Andrea, Marziano, Mariagrazia, Memo, Maurizio, Uberti, Daniela Letizia   +4 more
core   +1 more source

Serum Levels of Antibodies to Advanced Glycation End Products in Patients with Type 2 Diabetes Mellitus and Hypertension [PDF]

Folia Medica, 2020
Background and Aims: Proteins containing advanced glycation end products are highly immunogenic and anti-advanced glycation end products antibodies (anti-AGEs antibodies) are found in the sera of diabetics.Materials and methods: Enzyme-linked ...
Asparuh Nikolov, Alexander Blazhev, Maria Tzekova, Konstantin Kostov, Nikola Popovski   +4 more
doaj   +3 more sources