Results 41 to 50 of about 8,796,374 (289)

How Can Diet Affect the Accumulation of Advanced Glycation End-Products in the Human Body?

Foods, 2016
The accumulation of advanced glycation end products (AGEs) is associated with the complications of diabetes, kidney disease, metabolic disorders and degenerative diseases. It is recognized that the pool of glycation products found in the human body comes
Axel Guilbaud, Celine Niquet-Leridon, Eric Boulanger, Frederic J. Tessier   +3 more
doaj   +1 more source

Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay

Cogent Food & Agriculture, 2021
Glycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs).
Alpana Pande, Lakshmi Mundkur, Anurag Pande, Sarang Bani, Muhammed Majeed   +4 more
doaj   +1 more source

Advanced Glycation End Products in Age-related Macular Degeneration [PDF]

Archives of Ophthalmology, 1998
To investigate the localization of N epsilon-(carboxymethyl)lysine (CML), a component and major immunologic epitope of advanced glycation end products, in aged eyes and choroidal neovascular membranes (CNVMs) surgically excised from eyes with age-related macular degeneration.Immunohistochemistry for CML was performed using 8 snap-frozen, surgically ...
T, Ishibashi, T, Murata, M, Hangai, R, Nagai, S, Horiuchi, P F, Lopez, D R, Hinton, S J, Ryan   +7 more
openaire   +2 more sources

Pyridoxamine ameliorates the effects of advanced glycation end products on subtotal nephrectomy induced chronic renal failure rats

, 2014
Advanced glycation end products (AGEs) contribute to the pathogenesis of renal diseases and have become a new therapeutic target for treatment. Chronic renal failure (CRF) is the end-stage of chronic renal diseases and highly associated with increased ...
Chuang, Yao-Chen;Wu, Ming-Shiou;Wu, Tai-Hsien;Su, Yi-Kai;Lee, Yi-Min, 吳明修   +1 more
core   +1 more source

Advanced Glycation End Products and Inflammation in Type 1 Diabetes Development

, 2022
Type 1 diabetes (T1D) is an autoimmune disease in which the β-cells of the pancreas are attacked by the host’s immune system, ultimately resulting in hyperglycemia. It is a complex multifactorial disease postulated to result from a combination
Rani O. Whiddett, Whiddett, Rani O., Fotheringham, Amelia K, Chenping Du, Whiddett, Rani O, Chen Chen, Josephine M. Forbes, Du, Chenping, Chen, Chen, Buckle, Irina, Forbes, Josephine M, Fotheringham, Amelia K., Forbes, Josephine M., Irina Buckle, Amelia K. Fotheringham   +14 more
core   +1 more source

Enrichment and analysis of glycated proteins

Reviews in Analytical Chemistry, 2022
Glycation is a spontaneous post-translational modification of lysine, arginine, and the N-terminus of proteins. Protein glycation is closely related to the pathogenesis of human diseases, including diabetes, Alzheimer’s disease, renal disease, and cancer.
Cho Seonghyeon, Duong Van-An, Mok Jeong-Hun, Joo Minjoong, Park Jong-Moon, Lee Hookeun   +5 more
doaj   +1 more source

Glycation at the Crossroads of Disease Pathogenesis: Mechanistic Insights and Therapeutic Frontiers

Diseases
Protein glycation is a nonenzymatic modification that links sugar chemistry to molecular aging and chronic disease. Sequential reactions involving Schiff bases, Amadori products, and reactive α dicarbonyl intermediates generate advanced glycation end ...
Sneha Krishnamoorthi, Rupachandra Saravanakumar, Vivek Kumar   +2 more
doaj   +1 more source

Pinocembrin Protects from AGE-Induced Cytotoxicity and Inhibits Non-Enzymatic Glycation in Human Insulin

Cells, 2019
Advanced glycation end products (AGEs) are the end products of the glycation reaction and have a great importance in clinical science for their association with oxidative stress and inflammation, which play a major role in most chronic diseases, such as ...
Margherita Borriello, Clara Iannuzzi, Ivana Sirangelo   +2 more
doaj   +1 more source

AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBATAN PEMBENTUKKAN AGEs (ADVANCED GLYCATION END PRODUCTS) EKSTRAK KULIT BUAH PISANG GOROHO (Musa acuminate) [PDF]

, 2018
AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBATAN PEMBENTUKKAN AGEs (ADVANCED GLYCATION END PRODUCTS) EKSTRAK KULIT BUAH PISANG GOROHO (Musa acuminate)Jane Beatrix Rety Kowaas1), Edi Suryanto2), Defny Silvia Wewengkang3)1)Program studi Farmasi FMIPA Unsrat ...
Kowaas, Jane B.R.
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source