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Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

open access: yesFrontiers in Molecular Biosciences, 2022
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels.
Misganaw Asmamaw Mengstie   +7 more
doaj   +4 more sources

Advanced Glycation End Products and Psoriasis

open access: yesVaccines, 2023
Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli   +2 more
doaj   +4 more sources

Increased concentration of two different advanced glycation end-products detected by enzyme immunoassays with new monoclonal antibodies in sera of patients with rheumatoid arthritis [PDF]

open access: yesBMC Musculoskeletal Disorders, 2010
Background Levels of pentosidine (representative of advanced glycation end-products) in sera of patients with rheumatoid arthritis are increased when compared with sera of other diagnoses or healthy controls.
Vilím Vladimír   +2 more
doaj   +3 more sources

Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives

open access: yesBiomolecules, 2022
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids.
Mariyam Khalid, G. Petroianu, A. Adem
semanticscholar   +3 more sources

Advanced Glycation End Products in Health and Disease

open access: yesMicroorganisms, 2022
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are ...
V. Prakash Reddy   +2 more
doaj   +2 more sources

Advanced Glycation End Products in Disease Development and Potential Interventions. [PDF]

open access: yesAntioxidants (Basel)
Advanced glycation end products (AGEs) are a group of compounds formed through non-enzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids.
Zhang Y, Zhang Z, Tu C, Chen X, He R.
europepmc   +2 more sources

Role of advanced glycation end products in cellular signaling

open access: yesRedox Biology, 2014
Improvements in health care and lifestyle have led to an elevated lifespan and increased focus on age-associated diseases, such as neurodegeneration, cardiovascular disease, frailty and arteriosclerosis.
Christiane Ott   +5 more
doaj   +2 more sources

Sex-specific differences of advanced glycation end products in diabetes [PDF]

open access: yesNutrition & Diabetes
Advanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig   +5 more
doaj   +2 more sources

The effect of Galega officinalis L. extract on the content of the advanced glycation end products and their receptors in rat leukocytes under experimental diabetes mellitus

open access: yesБіологічні студії, 2021
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak   +2 more
doaj   +1 more source

Advanced glycation end products and cognitive impairment in schizophrenia.

open access: yesPLoS ONE, 2021
Advanced glycation end products play a key role in the pathophysiology of schizophrenia. Cognitive impairment is one of the central features of schizophrenia; however, the association between advanced glycation end products and cognitive impairment ...
Akiko Kobori   +17 more
doaj   +1 more source

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