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Advanced Glycation End Products and Psoriasis

Vaccines, 2023
Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni   +2 more
doaj   +3 more sources

Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

Frontiers in Molecular Biosciences, 2022
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels.
Misganaw Asmamaw Mengstie, Endeshaw Chekol Abebe, Awgichew Behaile Teklemariam, Anemut Tilahun Mulu, Melaku Mekonnen Agidew, Muluken Teshome Azezew, Edgeit Abebe Zewde, Assefa Agegnehu Teshome   +7 more
doaj   +3 more sources

Advanced glycation end‐products and the kidney [PDF]

European Journal of Clinical Investigation, 2010
Eur J Clin Invest 2010; 40 (8): 742–755AbstractBackground Advanced glycation end‐products (AGEs) are increased in situations with hyperglycemia and oxidative stress such as diabetes mellitus. They are products of nonenzymatic glycation and oxidation of proteins and lipids.
Martin Busch
exaly   +3 more sources

Advanced Glycation End Products in Health and Disease

Microorganisms, 2022
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are ...
V. Prakash Reddy, Puspa Aryal, Emmanuel K. Darkwah   +2 more
doaj   +3 more sources

The Role of Advanced Glycation End Products on Dyslipidemia [PDF]

Metabolites, 2023
Disorders of lipoprotein metabolism and glucose homeostasis are common consequences of insulin resistance and usually co-segregate in patients with metabolic syndrome and type 2 diabetes mellitus (DM).
Jelena Vekic, Sanja Vujcic, Biljana Bufan, Dragana Bojanin, Khamis Al-Hashmi, Khaild Al-Rasadi, Anca Pantea Stoian, Aleksandra Zeljkovic, Manfredi Rizzo   +8 more
doaj   +5 more sources

Skin Autofluorescence–Indicated Advanced Glycation End Products as Predictors of Cardiovascular and All‐Cause Mortality in High‐Risk Subjects: A Systematic Review and Meta‐analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Chronic deposits of advanced glycation end products produced by enzymatic glycation have been suggested as predictors of atherosclerotic‐related disorders.
Ivan Cavero‐Redondo, Alba Soriano‐Cano, Celia Álvarez‐Bueno, Pedro G. Cunha, Jose A. Martínez‐Hortelano, Miriam Garrido‐Miguel, Carlos Berlanga‐Macías, Vicente Martínez‐Vizcaíno   +7 more
doaj   +3 more sources

Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Aortic stenosis (AS) is highly prevalent in patients with atherosclerotic cardiovascular disease. Advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) play a pivotal role for vascular calcification in atherosclerosis.
Kosuke Saku, Nobuhiro Tahara, Tohru Takaseya, Hiroyuki Otsuka, Kazuyoshi Takagi, Takahiro Shojima, Yusuke Shintani, Yasuyuki Zaima, Satoshi Kikusaki, Tomofumi Fukuda, Atsunobu Oryoji, Yuri Nishino, Takanori Matsui, Tatsuyuki Kakuma, Jun Akiba, Yoshihiro Fukumoto, Sho‐ichi Yamagishi, Hiroyuki Tanaka   +17 more
doaj   +3 more sources

Sex-specific differences of advanced glycation end products in diabetes [PDF]

Nutrition & Diabetes
Advanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig, Julia Decker, Leticia Prates Roma, Stefan Schunk, Emmanuel Ampofo, Sandra Rother   +5 more
doaj   +2 more sources

The effect of Galega officinalis L. extract on the content of the advanced glycation end products and their receptors in rat leukocytes under experimental diabetes mellitus

Біологічні студії, 2021
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak, H. Ya. Hachkova, N. O. Sybirna   +2 more
doaj   +1 more source

Advanced glycation end products and cognitive impairment in schizophrenia.

PLoS ONE, 2021
Advanced glycation end products play a key role in the pathophysiology of schizophrenia. Cognitive impairment is one of the central features of schizophrenia; however, the association between advanced glycation end products and cognitive impairment ...
Akiko Kobori, Mitsuhiro Miyashita, Yasuhiro Miyano, Kazuhiro Suzuki, Kazuya Toriumi, Kazuhiro Niizato, Kenichi Oshima, Atsushi Imai, Yukihiro Nagase, Akane Yoshikawa, Yasue Horiuchi, Syudo Yamasaki, Atsushi Nishida, Satoshi Usami, Shunya Takizawa, Masanari Itokawa, Heii Arai, Makoto Arai   +17 more
doaj   +1 more source