Results 1 to 10 of about 38,510 (295)

A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages

Diabetes & Vascular Disease Research, 2020
Advanced glycation end-products, especially toxic advanced glycation end-products derived from glyceraldehyde (advanced glycation end-product-2) and glycolaldehyde (advanced glycation end-product-3), are biologically reactive compounds associated with ...
Takashi Nishinaka, Shuji Mori, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Tadashi Yoshino, Masahiro Nishibori, Hideo Takahashi   +7 more
doaj   +2 more sources

Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Aortic stenosis (AS) is highly prevalent in patients with atherosclerotic cardiovascular disease. Advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) play a pivotal role for vascular calcification in atherosclerosis.
Kosuke Saku, Nobuhiro Tahara, Tohru Takaseya, Hiroyuki Otsuka, Kazuyoshi Takagi, Takahiro Shojima, Yusuke Shintani, Yasuyuki Zaima, Satoshi Kikusaki, Tomofumi Fukuda, Atsunobu Oryoji, Yuri Nishino, Takanori Matsui, Tatsuyuki Kakuma, Jun Akiba, Yoshihiro Fukumoto, Sho‐ichi Yamagishi, Hiroyuki Tanaka   +17 more
doaj   +3 more sources

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Li, Jiao, Philip R, Taylor, Stephanie J, Weinstein, Barry I, Graubard, Jarmo, Virtamo, Demetrius, Albanes, Rachael Z, Stolzenberg-Solomon   +6 more
openaire   +3 more sources

Involvement of the receptor for advanced glycation end products in liver transplantation

Annals of Hepatology, 2015
Background and aim. Receptor for advanced glycation end products (RAGE) blockade by a soluble form of RAGE (sRAGE) appears to be protective against hepatocellular death and necrosis after I/R injury.
Teresa Navarra, Paolo De Simone, Serena Del Turco, Franco Filipponi, Giuseppina Basta   +4 more
doaj   +5 more sources

The effect of Galega officinalis L. extract on the content of the advanced glycation end products and their receptors in rat leukocytes under experimental diabetes mellitus

Біологічні студії, 2021
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak, H. Ya. Hachkova, N. O. Sybirna   +2 more
doaj   +1 more source

The Role of Advanced Glycation End Products in Diabetic Vascular Complications [PDF]

Diabetes & Metabolism Journal, 2018
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues.
Sang Youl Rhee, Young Seol Kim
doaj   +1 more source

Expression of advanced glycation end products and receptors in gingival tissues of patients with noninsulin-dependent diabetes mellitus-associated periodontitis

Journal of Dental Sciences, 2023
Background/purpose: Advanced glycation end products (AGEs) are known to accumulate in the periodontal tissues of patients with diabetes mellitus (DM). Through this study, we aimed to investigate the distribution of AGEs and the receptor of AGEs (RAGE) in
Ya-Han Chang, Chen-Ling Huang, An-Tsz Hsieh, Chia-Ai Jao, Hsein-Kun Lu   +4 more
doaj   +1 more source

Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts

Translational Oncology, 2022
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits, Pamela Woods, Lourdes M. Nogueira, Demarcus D. Woolfork, Courtney E. Lloyd, Andrew Baldwin, Callan C. Frye, Kendell D. Peterson, Sean D. Cosh, Qi-Jin Guo, Laura S. Spruill, Michael B. Lilly, Kristi Helke, Hong Li, George S. Hanna, Mark T. Hamann, Courtney Thomas, Mahtabuddin Ahmed, Monika B. Gooz, Victoria J. Findlay, David P. Turner   +20 more
doaj   +1 more source

The Receptor for Advanced Glycation End Products (RAGE) and the Lung [PDF]

Journal of Biomedicine and Biotechnology, 2010
The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules. As a pattern-recognition receptor capable of binding a diverse range of ligands, it is typically expressed at low levels under normal physiological conditions in the majority of tissues.
BUCKLEY, STEPHEN, EHRHARDT, CARSTEN
openaire   +3 more sources

Receptor for advanced glycation end products (RAGE) as a novel biomarker for differentiating drowning from postmortem submersion [PDF]

Minia Journal of Medical Research, 2023
Background and objective: Drowning is the death caused by fluid blocking the airway leading asphyxiation. One of the most difficult challenges in forensic medicine is making the diagnosis of drowning.
mariem shafek Keryakous, Mohamed Hashem, Eman Hassan, Dalia Ail   +3 more
doaj   +1 more source