Results 21 to 30 of about 82,871,848 (297)

A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages

Diabetes & Vascular Disease Research, 2020
Advanced glycation end-products, especially toxic advanced glycation end-products derived from glyceraldehyde (advanced glycation end-product-2) and glycolaldehyde (advanced glycation end-product-3), are biologically reactive compounds associated with ...
Takashi Nishinaka, Shuji Mori, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Tadashi Yoshino, Masahiro Nishibori, Hideo Takahashi   +7 more
doaj   +1 more source

Role of advanced glycation end products on vascular smooth muscle cells under diabetic atherosclerosis

Frontiers in Endocrinology, 2022
Atherosclerosis (AS) is a chronic inflammatory disease and leading cause of cardiovascular diseases. The progression of AS is a multi-step process leading to high morbidity and mortality. Hyperglycemia, dyslipidemia, advanced glycation end products (AGEs)
Lin Mao, Ruili Yin, Longyan Yang, Dong Zhao   +3 more
doaj   +1 more source

Participation of the Receptor for Advanced Glycation End Products in Efferocytosis [PDF]

The Journal of Immunology, 2011
Abstract Clearance of apoptotic cells by macrophages and other phagocytic cells, called efferocytosis, is a central process in the resolution of inflammation. Although the receptor for advanced glycation end products (RAGE) has been shown to participate in a variety of acute and chronic inflammatory processes in the lungs and other ...
Arnaud, Friggeri, Sami, Banerjee, Subrata, Biswas, Andressa, de Freitas, Gang, Liu, Angelika, Bierhaus, Edward, Abraham   +6 more
openaire   +2 more sources

Consequences of the interaction of amyloid beta with amyloid binding alcohol dehydrogenase and the receptor for advanced glycation end products [PDF]

, 2008
Amyloid beta (Aβ) has been postulated to be the principle initiator of the pathogenesis of Alzheimer’s disease (AD). Therefore, understanding the underlying mechanisms of Aβ induced neurotoxicity in the early stages of AD would be essential for finding ...
Ren, Yimin
core   +2 more sources

Advanced Glycation End Products and Receptor for Advanced Glycation End Products in AA Amyloidosis

The American Journal of Pathology, 2003
Advanced glycation end products (AGEs) may be involved in either amyloidogenesis or complications related to amyloid. We hypothesized that AGEs may influence the pathogenesis of AA amyloidosis, and investigated the spatial and temporal relationship between AGEs, carboxy methyl lysine (CML), the AGE receptor (RAGE), and AA amyloid in humans and mice ...
Christoph, Röcken, Rosemarie, Kientsch-Engel, Sophie, Mansfeld, Barbara, Stix, Kay, Stubenrauch, Bernd, Weigle, Frank, Bühling, Mona, Schwan, Wolfgang, Saeger   +8 more
openaire   +3 more sources

Association between advanced glycation end products and impaired fasting glucose : results from the SALIA study [PDF]

, 2015
Advanced glycation end products (AGEs) may contribute to the development of type 2 diabetes and related complications, whereas their role in the early deterioration of glycaemia is unknown.
Annette Peßler, Thomas Henle, Vierkötter, Andrea, Roden, Michael, Juliane Freund, Ursula Krämer, Schulte, Thomas, Michael Hellwig, Tamara Schikowski, Mohammad Vossoughi, Christian Luckhaus, Christian Herder, Tom Teichert, Luckhaus, Christian, Vossoughi, Mohammad, Thomas Schulte, Barbara Hoffmann, Schikowski, Tamara, Krämer, Ursula, Sugiri, Dorothea, Dorothea Sugiri, Hoffmann, Barbara, Hellwig, Michael, Anne Hellwig, Andrea Vierkötter, Henle, Thomas, Michael Roden, Freund, Juliane, Teichert, Tom, Hellwig, Anne, Peßler, Annette, Herder, Christian   +31 more
core   +2 more sources

Advanced Glycation End-Products (AGEs) and Their Soluble Receptor (sRAGE) in Women Suffering from Systemic Lupus Erythematosus (SLE)

Cells, 2021
Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak, Brygida Przywara-Chowaniec, Aleksandra Damasiewicz-Bodzek, Dominika Blachut, Ewa Nowalany-Kozielska, Krystyna Tyrpień-Golder   +5 more
doaj   +1 more source

Vitamin D and advanced glycation end products and their receptors

Pharmacological Research, 2020
Advanced glycation end products (AGEs) are destructive molecules in the body that, at high levels, contribute to the progression of various chronic diseases. Numerous studies have suggested a modifying effect of vitamin D on AGEs and their receptors. This study sought to summarize the effects of vitamin D on AGEs and their receptors, including receptor
Sorayya, Kheirouri, Mohammad, Alizadeh
openaire   +2 more sources

HMGB-1 - a novel mediator of inflammatory-induced renal epithelial mesenchymal transition [PDF]

, 2010
Background: High mobility group box protein 1 (HMGB-1) is a chromatin binding protein that bends DNA thereby facilitating gene transcription. HMGB-1 has also been observed as an extracellular secreted protein in serum of patients with sepsis and has ...
Ryan, Michael P., Michael P. Ryan, Slattery, Craig, Tara McMorrow, Nolan, Stephen, Ronan Feighery, Craig Slattery, Feighery, Ronan, Stephen Nolan, Julie Lynch, Lynch, Julie, McMorrow, Tara   +11 more
core   +1 more source

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE) [PDF]

Journal of Clinical Investigation, 2001
Tubulointerstitial disease, a prominent phenomenon in diabetic nephropathy, correlates with decline in renal function. The underlying pathogenic link between chronic hyperglycemia and the development of tubulointerstitial injury has not been fully elucidated, but myofibroblast formation represents a key step in the development of tubulointerstitial ...
Oldfield, MD, Bach, LA, Forbes, JM, Nikolic-Paterson, D, McRobert, A, Thallas, V, Atkins, RC, Osicka, T, Jerums, G, Cooper, ME   +9 more
openaire   +5 more sources