Results 41 to 50 of about 38,510 (295)

Elevated level of the soluble receptor for advanced glycation end-products involved in sarcopenia: an observational study

BMC Geriatrics, 2021
Background The soluble receptor for advanced glycation end products (sRAGE) has been proposed to serve as a marker for disease severity, but its role in sarcopenia, an age-related progressive loss of muscle mass and function, remains elusive.
Shou-En Wu, Yi-Lin Chiu, Tung-Wei Kao, Wei-Liang Chen   +3 more
doaj   +1 more source

RAGE is a critical factor of sex-based differences in age-induced kidney damage

Frontiers in Physiology, 2023
Introduction: Advanced glycation end products (AGEs) are a heterogeneous group of molecules with potential pathophysiological effects on the kidneys.
Seerat Bajwa, Alexander Luebbe, Ngoc Dong Nhi Vo, Eva-Maria Piskor, Christian Kosan, Gunter Wolf, Ivonne Loeffler   +6 more
doaj   +1 more source

Advanced glycation end products and their receptor contribute to ovarian ageing [PDF]

Human Reproduction, 2013
Do advanced glycation end products (AGE) and the receptor for advanced glycation end products (RAGE) affect the cells of the human ovarian follicle?AGE accumulate on the surface of ovarian granulosa-lutein (GL) cells and monocytes by binding to RAGE and other receptors with possible functional effects on these cells.AGE and RAGE are expressed in ...
Mette Haug, Stensen, Tom, Tanbo, Ritsa, Storeng, Peter, Fedorcsak   +3 more
openaire   +2 more sources

Advanced Glycation End Products and Inflammation in Type 1 Diabetes Development

, 2022
Type 1 diabetes (T1D) is an autoimmune disease in which the β-cells of the pancreas are attacked by the host’s immune system, ultimately resulting in hyperglycemia. It is a complex multifactorial disease postulated to result from a combination
Rani O. Whiddett, Whiddett, Rani O., Fotheringham, Amelia K, Chenping Du, Whiddett, Rani O, Chen Chen, Josephine M. Forbes, Du, Chenping, Chen, Chen, Buckle, Irina, Forbes, Josephine M, Fotheringham, Amelia K., Forbes, Josephine M., Irina Buckle, Amelia K. Fotheringham   +14 more
core   +1 more source

Protein glycoxidation in neuropsychiatric disorders—from basic research to clinical practice

Redox Biology
This review integrates current findings on protein glycation, glycoxidation, and carbonyl stress in selected neurodegenerative and neuropsychiatric disorders, with a particular focus on mechanistic pathways relevant to Alzheimer's disease (AD), Parkinson'
Wiktor Orlof, Mateusz Maciejczyk
doaj   +1 more source

HMGB-1 - a novel mediator of inflammatory-induced renal epithelial mesenchymal transition

, 2010
Background: High mobility group box protein 1 (HMGB-1) is a chromatin binding protein that bends DNA thereby facilitating gene transcription. HMGB-1 has also been observed as an extracellular secreted protein in serum of patients with sepsis and has ...
Ryan, Michael P., Michael P. Ryan, Slattery, Craig, Tara McMorrow, Nolan, Stephen, Ronan Feighery, Craig Slattery, Feighery, Ronan, Stephen Nolan, Julie Lynch, Lynch, Julie, McMorrow, Tara   +11 more
core   +1 more source

Circulating Ligands of the Receptor for Advanced Glycation End Products and the Soluble Form of the Receptor Modulate Cardiovascular Cell Apoptosis in Diabetes

Molecules, 2020
We determined whether plasma concentrations of the receptor for advanced glycation end products (RAGE) and the soluble (s) form of RAGE (sRAGE) in healthy individuals and patients with type 2 diabetes (T2D) modulate vascular remodeling.
James N. Tsoporis, Erifili Hatziagelaki, Sahil Gupta, Shehla Izhar, Vasileos Salpeas, Anastasia Tsiavou, Angelos G. Rigopoulos, Andreas S. Triantafyllis, John C. Marshall, Thomas G. Parker, Ioannis K. Rizos   +10 more
doaj   +1 more source

The impact of advanced glycation end products and their receptors on the development and prognosis of colorectal cancer

BMC Cancer
Purpose The purpose of this study was to analyze whether advanced glycation end products (AGEs) and their receptors had an impact on the development and prognosis of colorectal cancer (CRC).
Li-Juan Wang, Xiao-Yu Liu, Can Tan, Zi-wei Wang, Yong Cheng   +4 more
doaj   +1 more source

Enhanced expression of receptor for advanced glycation end-products is associated with low circulating soluble isoforms of the receptor in Type 2 diabetes

, 2010
The sRAGE [soluble RAGE (receptor for advanced glycation end-products)] lack the transmembrane and cytoplasmic domain of the full-length receptor and can function as a decoy for RAGE ligands.
D. John Betteridge, Lin Leng, Richard Bucala, Tam, XHL, Bucala, R, Leng, L, Betteridge, DJ, Sammy W. M. Shiu, Kathryn C. B. Tan, Tan, KCB, Xystus H. L. Tam, Shiu, SWM   +11 more
core   +1 more source

Engineered AuNPs/fMWCNT Nanocomposite Electrodes for High‐Sensitivity Methylglyoxal Sensing in Saliva and Sweat for Non‐Invasive Diabetes Monitoring

Advanced Healthcare Materials, EarlyView.
An AuNPs/fMWCNT nanocomposite‐modified screen‐printed carbon electrode was engineered via sequential electrodeposition and integrated into a 3D‐printed microfluidic platform for ultrasensitive methylglyoxal detection. The non‐invasive sensing platform enables rapid analysis in saliva and sweat, highlighting strong potential for wearable point‐of‐care ...
Ahadul Amin Soshi, Md Younus Ali, Dadbeh Pazuki, Matiar M.R. Howlader   +3 more
wiley   +1 more source