Results 11 to 20 of about 59,203 (302)

Involvement of the receptor for advanced glycation end products in liver transplantation

Annals of Hepatology, 2015
Background and aim. Receptor for advanced glycation end products (RAGE) blockade by a soluble form of RAGE (sRAGE) appears to be protective against hepatocellular death and necrosis after I/R injury.
Teresa Navarra, Paolo De Simone, Serena Del Turco, Franco Filipponi, Giuseppina Basta   +4 more
doaj   +5 more sources

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Li, Jiao, Philip R, Taylor, Stephanie J, Weinstein, Barry I, Graubard, Jarmo, Virtamo, Demetrius, Albanes, Rachael Z, Stolzenberg-Solomon   +6 more
openaire   +2 more sources

Assessment of Advanced Glycation End Products and Receptors and the Risk of Dementia [PDF]

JAMA Network Open, 2021
Advanced glycation end products (AGEs) and their receptor (RAGE) are implicated in the pathophysiological processes of dementia and potentially underlie the association of diabetes with neurodegeneration. However, longitudinal studies examining this association are lacking.To determine whether markers of the AGE-RAGE system are associated with ...
Chen, Jinluan, Mooldijk, Sanne, Licher, Silvan, Waqas, Komal, Ikram, Kamran, Uitterlinden, André, Zillikens, M.C., Ikram, Arfan   +7 more
openaire   +2 more sources

Advanced Glycation End Product Recognition by the Receptor for AGEs [PDF]

Structure, 2011
Nonenzymatic protein glycation results in the formation of advanced glycation end products (AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's disease, and cancer. AGEs mediate their effects primarily through a receptor-dependent pathway in which AGEs bind to a specific cell surface associated receptor, the ...
Xue, Jing, Rai, Vivek, Singer, David, Chabierski, Stefan, Xie, Jingjing, Reverdatto, Sergey, Burz, David S., Schmidt, Ann Marie, Hoffmann, Ralf, Shekhtman, Alexander   +9 more
openaire   +2 more sources

The Receptor for Advanced Glycation End Products (RAGE) and the Lung [PDF]

Journal of Biomedicine and Biotechnology, 2010
The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules. As a pattern-recognition receptor capable of binding a diverse range of ligands, it is typically expressed at low levels under normal physiological conditions in the majority of tissues.
BUCKLEY, STEPHEN, EHRHARDT, CARSTEN
openaire   +3 more sources

Role of advanced glycation end products on vascular smooth muscle cells under diabetic atherosclerosis

Frontiers in Endocrinology, 2022
Atherosclerosis (AS) is a chronic inflammatory disease and leading cause of cardiovascular diseases. The progression of AS is a multi-step process leading to high morbidity and mortality. Hyperglycemia, dyslipidemia, advanced glycation end products (AGEs)
Lin Mao, Ruili Yin, Longyan Yang, Dong Zhao   +3 more
doaj   +1 more source

Methylglyoxal-dependent glycative stress and deregulation of SIRT1 functional network in the ovary of PCOS mice [PDF]

, 2020
Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility.
Amicarelli, F, Cristiano, L, D'Alessandro, AM, Emidio, GD, Falone, S, Nottola, S, Palmerini, MG, Placidi, M, Rea, F, Rossi, G, Tatone, C   +10 more
core   +1 more source

Participation of the Receptor for Advanced Glycation End Products in Efferocytosis [PDF]

The Journal of Immunology, 2011
Abstract Clearance of apoptotic cells by macrophages and other phagocytic cells, called efferocytosis, is a central process in the resolution of inflammation. Although the receptor for advanced glycation end products (RAGE) has been shown to participate in a variety of acute and chronic inflammatory processes in the lungs and other ...
Arnaud, Friggeri, Sami, Banerjee, Subrata, Biswas, Andressa, de Freitas, Gang, Liu, Angelika, Bierhaus, Edward, Abraham   +6 more
openaire   +2 more sources

Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]

, 2018
The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A, Currier, Judith S, Danoff, Ann, Kelesidis, Theodoros, Kendall, Michelle A, Schmidt, Ann Marie   +5 more
core   +1 more source

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products [PDF]

, 2014
Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE).
A Bierhaus, AL Miller, AM Schmidt, B Rippe, C Cheng, C Chuong, CN Pace, D Frommhold, DI Sternberg, DS Pisetsky, G Marsche, H Fehrenbach, H Vlassara, H Vlassara, H Zhang, HC Volz, J Brett, J Steiner, J Xie, Jan J. Enghild, JH Boyd, JL Wautier, JM Englert, JM Englert, JR Klune, Judson M. Englert, K Dahlin, K Kataoka, KC Sourris, Lasse Ramsgaard, Lauren T. Crum, LE Hanford, Louis J. Sparvero, M Neeper, M Shirasawa, MA Hofmann, Michael T. Lotze, MT Goova, N Demling, Neale S. Mason, P Andrews, P Teismann, Pavle S. Milutinovic, R Pullerits, R Ramasamy, RH Hastings, RH Hastings, RM Effros, S Du Yan, S Mizumoto, S Muhammad, S Zeng, T Do, T Wendt, TA John, Tim D. Oury, William R. Abrams, Y Abdiche, Z Sarkany   +58 more
core   +8 more sources