Results 11 to 20 of about 120,642 (347)
Advanced glycation end-products: a review [PDF]
Diabetologia, 2001 Advanced glycation end-products are a complex and heterogeneous group of compounds that have been implicated in diabetes related complications. At present it is not known if they are the cause or the consequence of the complications observed. We discuss the chemistry of advanced glycated end-product formation and their patho-biochemistry particularly ...
R. Singh +3 more
semanticscholar +5 more sources
Cells, 2022 Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse group of compounds formed either exogeneously or endogeneously on the course of various pathways in the human body.
Aleksandra Twarda-Clapa +3 more
semanticscholar +3 more sources
Toxicity of advanced glycation end products (Review)
Biomedical Reports, 2021 Advanced glycation end-products (AGEs) are proteins or lipids glycated nonenzymatically by glucose, or other reducing sugars and their derivatives, such as glyceraldehyde, glycolaldehyde, methyloglyoxal and acetaldehyde.
Aleksandra Kuzan
semanticscholar +5 more sources
Advanced Glycation End Products and Diabetic Complications [PDF]
The Korean Journal of Physiology & Pharmacology, 2014 During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation.
Varun Singh +3 more
semanticscholar +3 more sources
Comprehensive Reviews in Food Science and Food Safety, 2020 Dietary advanced glycation end products (dAGEs) are complex and heterogeneous compounds derived from nonenzymatic glycation reactions during industrial processing and home cooking. There is mounting evidence showing that dAGEs are closely associated with
Qiaozhi Zhang, Yanbo Wang, L. Fu
semanticscholar +3 more sources
Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus
Biomolecules, 2015 Type 2 diabetes mellitus (T2DM) is a very complex and multifactorial metabolic disease characterized by insulin resistance and β cell failure leading to elevated blood glucose levels.
Kerstin Nowotny +4 more
semanticscholar +3 more sources
Cell Metabolism, 2018 Accumulation of advanced glycation end products (AGEs) on nucleotides, lipids, and peptides/proteins are an inevitable component of the aging process in all eukaryotic organisms, including humans.
Jyotiska Chaudhuri +7 more
semanticscholar +3 more sources
Advanced glycation end‐products and the kidney [PDF]
European Journal of Clinical Investigation, 2010 Eur J Clin Invest 2010; 40 (8): 742–755AbstractBackground Advanced glycation end‐products (AGEs) are increased in situations with hyperglycemia and oxidative stress such as diabetes mellitus. They are products of nonenzymatic glycation and oxidation of proteins and lipids.
Martin, Busch +3 more
openaire +4 more sources
A Role for Advanced Glycation End Products in Molecular Ageing
International Journal of Molecular Sciences, 2023 Ageing is a composite process that involves numerous changes at the cellular, tissue, organ and whole-body levels. These changes result in decreased functioning of the organism and the development of certain conditions, which ultimately lead to an ...
K. Zgutka +3 more
semanticscholar +1 more source
Physiological Reports, 2022 Diabetes mellitus is associated with cardiovascular disease and cardiac arrhythmia. Accumulation of advanced glycation end products closely correlates with cardiovascular complications through mitochondrial dysfunction or oxidative stress and evoke ...
Yao‐Chang Chen +6 more
doaj +1 more source