Journal of Dental Sciences, 2023 Background/purpose: Advanced glycation end products (AGEs) are known to accumulate in the periodontal tissues of patients with diabetes mellitus (DM). Through this study, we aimed to investigate the distribution of AGEs and the receptor of AGEs (RAGE) in
Ya-Han Chang +4 more
doaj +1 more source
Advanced glycation end products [PDF]
Dermato-Endocrinology, 2012 Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire +2 more sources
NMR analysis of synthetic human serum albumin alpha-helix 28 identifies structural distortion upon amadori modification [PDF]
, 2005 The non-enzymatic reaction between reducing sugars and long-lived proteins in vivo results in the formation of glycation and advanced glycation end products, which alter the properties of proteins including charge, helicity, and their tendency to ...
Howard, Mark J. +1 more
core +1 more source
Advanced Glycation End-Products and Diabetic Neuropathy of the Retina
International Journal of Molecular Sciences, 2023 Diabetic retinopathy is a tissue-specific neurovascular impairment of the retina in patients with both type 1 and type 2 diabetes. Several pathological factors are involved in the progressive impairment of the interdependence between cells that consist ...
T. Oshitari
semanticscholar +1 more source
Association of advanced glycation end products in Dupuytren disease
Journal of Orthopaedic Surgery and Research, 2018 Background Advanced glycation end products are associated with aging, hyperglycemia, and oxidative stress. Accumulation of advanced glycation end products can cause various pathological conditions; however, the association of Dupuytren’s disease with ...
Fumiaki Takase +6 more
doaj +1 more source
Advanced Glycation End-Products and Their Effects on Gut Health
Nutrients, 2023 Dietary advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed when reducing sugars are heated with proteins, amino acids, or lipids at high temperatures for a prolonged period.
Kate Phuong-Nguyen +3 more
semanticscholar +1 more source
A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]
PLoS ONE, 2018 Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel +9 more
doaj +1 more source
Translational Oncology, 2022 The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits +20 more
doaj +1 more source
Advanced Glycation End-Products Suppress Mitochondrial Function and Proliferative Capacity of Achilles Tendon-Derived Fibroblasts [PDF]
, 2019 Debilitating cases of tendon pain and degeneration affect the majority of diabetic individuals. The high rate of tendon degeneration persists even when glucose levels are well controlled, suggesting that other mechanisms may drive tendon degeneration in ...
Cannon, Jason R. +8 more
core +2 more sources
Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]
, 2018 The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A +5 more
core +1 more source