Results 21 to 30 of about 120,642 (347)

The Role of Advanced Glycation End Products in Diabetic Vascular Complications [PDF]

Diabetes & Metabolism Journal, 2018
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues.
Sang Youl Rhee, Young Seol Kim
doaj   +1 more source

Advanced glycation end products, galectin-3, matrix metalloproteinase-9 activity in men with heart failure and concomitant benign prostatic hyperplasia with androgen deficiency

Medičnì Perspektivi, 2021
The aim was to evaluate serum levels of matrix metalloproteinases-9 activity, advanced glycation end products, galectin-3, C-reactive protein in men with heart failure and benign prostatic hyperplasiawith testosterone deficiency.
V.S. Nedzvetsky, O.Yu. Sirenko, V.A. Tkachenko, O.V. Kuryata   +3 more
doaj   +1 more source

Advanced glycation end products: sparking the development of diabetic vascular injury.

Circulation, 2006
Advanced glycation end products (AGEs) are proteins or lipids that become glycated after exposure to sugars. AGEs are prevalent in the diabetic vasculature and contribute to the development of atherosclerosis. The presence and accumulation of AGEs in many different cell types affect extracellular and intracellular structure and function.
Alison H. Goldin, J. Beckman, A. Schmidt, M. Creager   +3 more
semanticscholar   +3 more sources

Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury

Experimental and Molecular Medicine, 2021
Advanced glycation end products (AGEs) are potentially harmful and heterogeneous molecules derived from nonenzymatic glycation. The pathological implications of AGEs are ascribed to their ability to promote oxidative stress, inflammation, and apoptosis ...
W. Rungratanawanich, Ying Qu, Xin Wang, M. Essa, B. Song   +4 more
semanticscholar   +1 more source

Fingertip advanced glycation end products and psychotic symptoms among adolescents

npj Schizophrenia, 2021
Case control studies have suggested that advanced glycation end products play a key role in the pathophysiology of chronic schizophrenia. However, the longitudinal association between advanced glycation end products and psychotic symptoms among drug ...
Mitsuhiro Miyashita, Syudo Yamasaki, Shuntaro Ando, Kazuhiro Suzuki, Kazuya Toriumi, Yasue Horiuchi, Akane Yoshikawa, Atsushi Imai, Yukihiro Nagase, Yasuhiro Miyano, Tomoko Inoue, Kaori Endo, Yuko Morimoto, Masaya Morita, Tomoki Kiyono, Satoshi Usami, Yuji Okazaki, Toshiaki A. Furukawa, Mariko Hiraiwa-Hasegawa, Masanari Itokawa, Kiyoto Kasai, Atsushi Nishida, Makoto Arai   +22 more
doaj   +1 more source

Advanced Glycation End Products and Their Effect on Vascular Complications in Type 2 Diabetes Mellitus

Nutrients, 2022
Diabetes is well established as a chronic disease with a high health burden due to mortality or morbidity from the final outcomes of vascular complications. An increased duration of hyperglycemia is associated with abnormal metabolism. Advanced glycation
Jeongmin Lee, J. Yun, Seung-Hyun Ko
semanticscholar   +1 more source

Zinc against advanced glycation end products [PDF]

Clinical and Experimental Pharmacology and Physiology, 2018
SummaryAdvanced glycation end products (AGEs) are destructive compounds with pathogenic importance in age‐related chronic diseases. Zinc has antioxidant, anti‐inflammatory and anti‐apoptotic potential. This study aimed to summarize effects of zinc onAGEformation andAGE‐induced damaging agents.
Sorayya Kheirouri, Mohammad Alizadeh, Vahid Maleki   +2 more
openaire   +2 more sources

Predictive ability of serum advanced glycation end products at 11 to 13 weeks of gestation for early-onset preeclampsiaAJOG Global Reports at a Glance

AJOG Global Reports, 2022
BACKGROUND: Placental hypoxia and resultant oxidative stress have been associated with the development of preeclampsia. Oxidative stress promotes the formation of advanced glycation end products. OBJECTIVE: This study aimed to assess whether serum levels
Minako Goto, MD, Sho-ichi Yamagishi, MD, Takanori Matsui, PhD, Keiko Koide, MD, Hiroko Takita, MD, Mayumi Tokunaka, MD, Akihiko Sekizawa, MD   +6 more
doaj   +1 more source

Advanced Glycation End Products in the Skin: Molecular Mechanisms, Methods of Measurement, and Inhibitory Pathways

Frontiers in Medicine, 2022
Advanced glycation end products (AGEs) are a series of stable compounds produced under non-enzymatic conditions by the amino groups of biomacromolecules and the free carbonyl groups of glucose or other reducing sugars commonly produced by thermally ...
Chun-yu Chen, Jiaqi Zhang, Li Li, M. Guo, Yifan He, Yin-mao Dong, Hong Meng, Fan Yi   +7 more
semanticscholar   +1 more source

A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages

Diabetes & Vascular Disease Research, 2020
Advanced glycation end-products, especially toxic advanced glycation end-products derived from glyceraldehyde (advanced glycation end-product-2) and glycolaldehyde (advanced glycation end-product-3), are biologically reactive compounds associated with ...
Takashi Nishinaka, Shuji Mori, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Tadashi Yoshino, Masahiro Nishibori, Hideo Takahashi   +7 more
doaj   +1 more source