Results 21 to 30 of about 49,218 (259)

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Li, Jiao   +6 more
openaire   +2 more sources

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]

open access: yesPLoS ONE, 2018
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel   +9 more
doaj   +1 more source

Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts

open access: yesTranslational Oncology, 2022
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits   +20 more
doaj   +1 more source

Skin advanced glycation end-products evaluation in infants according to the type of feeding and mother’s smoking habits

open access: yesSAGE Open Medicine, 2016
Objectives: This study was conducted to assess whether formula-fed infants had increased skin advanced glycation end-products compared with breastfed ones.
Giovanni Federico   +3 more
doaj   +1 more source

Zinc against advanced glycation end products [PDF]

open access: yesClinical and Experimental Pharmacology and Physiology, 2018
SummaryAdvanced glycation end products (AGEs) are destructive compounds with pathogenic importance in age‐related chronic diseases. Zinc has antioxidant, anti‐inflammatory and anti‐apoptotic potential. This study aimed to summarize effects of zinc onAGEformation andAGE‐induced damaging agents.
Sorayya Kheirouri   +2 more
openaire   +2 more sources

Leukocytes in type 1 diabetes mellitus: the changes they undergo and induce

open access: yesБіологічні студії, 2022
As leukocytes represent cellular and humoral immunity at the same time, they are a vital part of every immune process. This also stands for autoimmune processes and disorders, such as diabetes, specifically type 1 diabetes mellitus.
О. М. Kuchurka   +4 more
doaj   +1 more source

Advanced Glycation End-Products in Skeletal Muscle Aging

open access: yesBioengineering, 2021
Advanced age causes skeletal muscle to undergo deleterious changes including muscle atrophy, fast-to-slow muscle fiber transition, and an increase in collagenous material that culminates in the age-dependent muscle wasting disease known as sarcopenia ...
Lucas C. Olson   +4 more
doaj   +1 more source

Association of Dietary Advanced Glycation End Products with Metabolic Syndrome in Young Mexican Adults

open access: yesMedicines, 2018
Background: Consumption of dietary advanced glycation end products is linked to metabolic syndrome. The objective was to describe the association between dietary advanced glycation end products intake and metabolic syndrome in young Mexican adults ...
Kenny Mendoza-Herrera   +5 more
doaj   +1 more source

Advanced Glycation End Products and Diabetic Complications [PDF]

open access: yesThe Korean Journal of Physiology & Pharmacology, 2014
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy ...
Singh, Varun Parkash   +3 more
openaire   +2 more sources

Advanced glycation end products [PDF]

open access: yesDermato-Endocrinology, 2012
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire   +2 more sources

Home - About - Disclaimer - Privacy