Results 171 to 180 of about 59,132 (205)

Expression of Receptor for Advanced Glycation End Products in Sarcoid Granulomas

American Journal of Respiratory and Critical Care Medicine, 2007
The receptor for advanced glycation end products (RAGE) engages a number of ligands implicated in inflammatory processes. The RAGE coding gene maps to the 6p21.32 region, close to the genes DRB1 and BTNL2, which are associated with sarcoidosis.We investigated a possible implication of RAGE in sarcoid granulomas.RAGE and major ligands (N-epsilon-carboxy-
CAMPO I, MORBINI P, ZORZETTO M, TINELLI C, BRUNETTA E, VILLA C, BOMBIERI C, CUCCIA M, AGOSTINI, CARLO, BOZZI V, FACOETTI A, FERRAROTTI I, MAZZOLA P, SCABINI R, SEMENZATO, GIANPIETRO CARLO, PIGNATTI PF, POZZI E, LUISETTI M.   +17 more
openaire   +4 more sources

Cellular signalling of the receptor for advanced glycation end products (RAGE)

Cellular Signalling, 2013
The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor which senses a variety of signalling molecules including advanced glycation end products (AGEs), HMGB1, S100/calgranulins, β-amyloid, phosphatidylserine, C3a and advanced oxidation protein products (AOPPs).
Jianling, Xie, José D, Méndez, Verna, Méndez-Valenzuela, María Montserrat, Aguilar-Hernández   +3 more
openaire   +2 more sources

Receptor for advanced glycation end products is protective during murine tuberculosis

Molecular Immunology, 2012
The development of active tuberculosis after infection with Mycobacterium tuberculosis is almost invariably associated with a persistent or transient state of relative immunodeficiency. The receptor for advanced glycation end products (RAGE) is a promiscuous receptor that is involved in pulmonary inflammation and infection.
Zoelen, M.A. van, Wieland, C.W., Windt, G.J. van der, Florquin, S., Nawroth, P.P., Bierhaus, A., Poll, T. van der   +6 more
openaire   +3 more sources

Role of receptor for advanced glycation end products in cardiogenic shock*

Critical Care Medicine, 2012
Activation of the receptor for advanced glycation end products by its ligands promotes inflammatory processes and tissue injury. The available evidence suggests that soluble forms of receptor for advanced glycation end products circulating in the plasma may neutralize the ligand-mediated damage by acting as a decoy.
Simina-Ramona, Selejan, Janine, Pöss, Lisa, Hewera, Andrey, Kazakov, Michael, Böhm, Andreas, Link   +5 more
openaire   +2 more sources

The receptor for advanced glycation end-products supports lung tissue biomechanics

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2013
The receptor for advanced glycation end-products (RAGE) and its soluble forms are predominantly expressed in lung but its physiological importance in this organ is not yet fully understood. Since RAGE acts as a cell adhesion molecule, we postulated its physiological importance in the respiratory mechanics.
Samiya, Al-Robaiy, Bettina, Weber, Andreas, Simm, Claudius, Diez, Paulina, Rolewska, Rolf-Edgar, Silber, Babett, Bartling   +6 more
openaire   +2 more sources

Receptor for Advanced Glycation End Product Expression in Experimental Diabetic Retinopathy

Annals of the New York Academy of Sciences, 2008
The advanced glycation end product (AGE)–receptor for AGE (RAGE) pathway is involved in the pathogenesis of diabetic microvascular damage. The special distribution of RAGE and its engagement has an impact on the development of diabetic retinopathy. In the present study, we used immunofluorescence and confocal laser microscopy to study RAGE expression ...
Wang, Yumei, Hagen, Filanziska Vom, Pfister, Frederick, Bierhaus, Angelika, Feng, Yuxi, Gans, Reinhold, Hammes, Hans-Peter   +6 more
openaire   +2 more sources

Receptor for advanced glycation end products in bacterial infection

Current Opinion in Infectious Diseases, 2012
Sepsis is still associated with excess morbidity and mortality worldwide, despite significant advances in critical care medicine. A novel approach is needed in the treatment of sepsis, one that will aim to correct the specific immunologic imbalance that is detrimental to the septic host.As receptor for advanced glycation end products (RAGE) is involved
Christaki, Eirini, Lazaridis, Nikolaos, Opal, Steven M., Christaki, Eirini, Lazaridis, Nikolaos, Opal, Steven M.   +5 more
openaire   +3 more sources

Receptor for advanced glycation end products polymorphisms in coronary artery ectasia

Gene
Although the implication of receptor of advanced glycation endproducts (RAGE) has been reported in coronary artery disease, its roles in coronary artery ectasia (CAE) have remained undetermined. Furthermore, the effect of RAGE polymorfisms were not well-defined in scope of soluble RAGE (sRAGE) levels.
Ezgi Irmak Aslan, Gulcin Ozkara, Onur Kilicarslan, Ozgur Selim Ser, Cem Bostan, Ahmet Yildiz, Ayca Diren Borekcioglu, Oguz Ozturk, Ozlem Kucukhuseyin, Hulya Yilmaz Aydogan   +9 more
openaire   +2 more sources

Receptor for Advanced Glycation End Products in Neuronal Pathophysiology

The receptor for advanced glycation end products (RAGE) is a multi-ligand receptor molecule expressed in the cells of the nervous system (neurons and glial cells). Compared to embryonic cells, RAGE expression is significantly decreased within the adult tissues, including the nervous system. Various RAGE ligands such as amyloidbeta peptide (Aβ-peptide),
Parth Malik, Ruma Rani, Tapan Kumar , Mukherjee   +2 more
openaire   +1 more source

Receptor for Advanced Glycation End Products in Pulmonary Diseases

The receptor for advanced glycation end products (RAGE) is characterized as a multi-ligand pattern recognition receptor molecule exhibiting physiologically profuse expression in the lung alveolar type 1 (AT-1) epithelial cell’s basolateral region. Advanced glycation end products (AGEs) are the most prominent among the multiple ligands of RAGE in lung ...
Parth Malik, Ruma Rani, Tapan Kumar Mukherjee   +2 more
openaire   +1 more source