Results 261 to 270 of about 409,522 (315)

Current management of neurotrophic receptor tyrosine kinase fusion-positive sarcoma: an updated review. [PDF]

Jpn J Clin Oncol
Kubota Y, Kawano M, Iwasaki T, Itonaga I, Kaku N, Ozaki T, Tanaka K.   +6 more
europepmc   +1 more source

Cellular Receptor Tyrosine Kinase Signaling Plays Important Roles in SARS-CoV-2 Infection. [PDF]

Pathogens
Sanchez S, Flannery BH, Murphy H, Huang Q, Ly H, Liang Y.   +5 more
europepmc   +1 more source

Neurotrophic Receptor Tyrosine Kinase 3 as a Prognostic Biomarker in Breast Cancer Using Bioinformatic Analysis. [PDF]

Medicina (Kaunas)
Choi J, Kim J, Jung YW, Park JH, Lee JH.
europepmc   +1 more source

Identification of C-mannosylation in a receptor tyrosine kinase AXL. [PDF]

Glycobiology
Mori K, Suzuki T, Waki U, Hayashi S, Kadono S, Kawahara R, Takeuchi M, Mizuta H, Dohmae N, Katayama R, Simizu S.   +10 more
europepmc   +1 more source

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Receptor tyrosine kinases

The FASEB Journal, 1992
A major process through which environmental information is transmitted into cells is via activation of protein tyrosine kinases. Receptor tyrosine kinases contain extracellular ligand recognition, single membrane spanning, and cytoplasmic protein tyrosine kinase domains. The cytoplasmic kinase core is flanked by regulatory segments,
D L, Cadena, G N, Gill
openaire   +2 more sources

Receptor tyrosine kinases and their targets

Current Opinion in Genetics & Development, 1994
One of the ways in which higher eukaryotes receive messages from the environment is via cell surface receptor tyrosine kinases. These are transmembrane proteins with an extracellular binding domain that specifies the growth factor with which it will interact, and an intracellular domain that encodes the tyrosine kinase.
openaire   +2 more sources

Receptor tyrosine kinase inhibitors in cancer

Cellular and Molecular Life Sciences, 2023
Targeted therapy is a new cancer treatment approach, involving drugs that particularly target specific proteins in cancer cells, such as receptor tyrosine kinases (RTKs) which are involved in promoting growth and proliferation, Therefore inhibiting these proteins could impede cancer progression.
Nasim, Ebrahimi, Elmira, Fardi, Hajarossadat, Ghaderi, Sahar, Palizdar, Roya, Khorram, Reza, Vafadar, Masoud, Ghanaatian, Fatemeh, Rezaei-Tazangi, Payam, Baziyar, Amirhossein, Ahmadi, Michael R, Hamblin, Amir Reza, Aref   +11 more
openaire   +2 more sources

Receptor tyrosine kinases and the regulation of hematopoiesis

Seminars in Immunology, 1995
The ongoing production of mature blood cells during the lifetime of an animal is vital for survival. Hematopoiesis is the complex process whereby a small population of pluripotential stem cells give rise to mature cell types with specialized functions.
R F, Paulson, A, Bernstein
openaire   +2 more sources

Tyrosine kinase receptor expression in thymomas

Journal of Cancer Research and Clinical Oncology, 2004
Promising new therapies for neoplasia include tyrosine kinase receptor antagonists. Tyrosine kinase oncogenes present an appealing anti-tumor drug target since they play an integral role in a variety of cellular responses including cell proliferation and differentiation.
John D, Henley, Oscar W, Cummings, Patrick J, Loehrer   +2 more
openaire   +2 more sources

Inhibitors of the insulin receptor tyrosine kinase

Pharmacology & Therapeutics, 1994
Insulin is a polypeptide hormone consisting of 51 amino acids. Insulin promotes a variety of anabolic enzymatic pathways and inhibits many catabolic enzymatic pathways involved in energy storage, as well as in synthesis of structural tissue proteins.
P R, Srinivas, G, Grunberger
openaire   +2 more sources