Results 111 to 120 of about 29,601 (261)
Delayed Loop Ileostomy Reversal Increases the Risk of Colitis and Clostridium difficile Infection
ANZ Journal of Surgery, EarlyView.Delayed loop ileostomy reversal is associated with increased post‐operative complications specifically colitis and Clostridium difficile colitis. The COVID‐19 pandemic caused a significant delay in ileostomy reversal timing. ABSTRACT Background Temporary loop ileostomy formation is a routine procedure performed to protect distal colorectal anastomosis.
Yan S. Tan +12 more
wiley +1 more source
Effects of gestational weight gain and HbA1C on fetal growth and birthweight in women with obesity
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Our results indicate that HbA1C measured in the third semester and the modifiable gestational weight gain are exposures with the potential to influence fetal growth and birthweight in this population of pregnant women with pBMI ≥35 kg/m2. Abstract Introduction Fetal growth and birthweight are influenced by various endogenous and exogenous factors ...
Maja Lecic Bonnichsen +5 more
wiley +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Peripherally derived adiponectin crosses the blood–brain barrier and targets severa0l brain regions. Adiponectin receptors are highly expressed in the hippocampus, and play a pro‐cognitive role as adiponectin markedly influences the functioning of hippocampal synapses.
Alexandra Soca +4 more
wiley +1 more source
Role of Adiponectin in prostate cancer
International Brazilian Journal of UrologyObesity is defined as a chronic and excessive growth of adipose tissue. It has been associated with a high risk for development and progression of obesity-associated malignancies, while adipokines may mediate this association.
Xiaobo Hu +5 more
doaj +1 more source
Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib +3 more
wiley +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
The FEBS Journal, EarlyView.Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Introduction Apical periodontitis (AP) is an inflammatory disease of the periapical tissues driven by host responses to endodontic infection, and systemic metabolic disturbances, such as high‐fat diet (HFD)–induced dysmetabolism, may exacerbate tissue destruction. This study aimed to determine how chronic HFD exposure alters periapical myeloid
Maryam Ghaffari +3 more
wiley +1 more source
Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective
Immunology, EarlyView.Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac +7 more
wiley +1 more source