Results 161 to 170 of about 29,601 (261)

Association Between a Body Shape Index and Epilepsy Among US Adults: Potential Indirect Pathway Through Depressive Symptoms

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background Epilepsy is a common and disabling brain disorder. Whether a body shape index (ABSI) is associated with epilepsy, and whether depressive symptoms may partly account for this association, remain unclear. Methods We analyzed 13,066 participants from the National Health and Nutrition Examination Survey 2013–2018.
Qiaoduan Feng, Xiujuan Mi, Hongbin Tang, Shaokun Yang, Can Wan, Jinsong You, Jun Tang   +6 more
wiley   +1 more source

Revisiting the multiple roles of T-cadherin and adiponectin in cardiovascular disease: from receptor function to exosome-mediated therapeutic potential. [PDF]

Ewha Med J
Kang IS.
europepmc   +1 more source

Correlation of the peripheral blood DNA methylation profile and immune‐related adverse events in patients with solid cancer treated with immune checkpoint inhibitors

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Baseline blood DNA methylation profiles predict early immune‐related adverse events across cancer types. A methylation‐based classifier demonstrated robust discriminatory performance and revealed enrichment of neuronal and developmental regulatory pathways, suggesting a systemic epigenetic predisposition to immune toxicity following immune checkpoint ...
Markus Kleinberger, Angelika Martina Starzer, Erwin Tomasich, Julia Maria Berger, Vincent Sunder‐Plassmann, Lynn Gottmann, Isabella Solano Henao, Martin Korpan, Josef Fuerst, Nikola Vladic, Cihan Ay, Helmuth Haslacher, Julia Furtner, Matthias Preusser, Gerwin Heller, Anna Sophie Berghoff   +15 more
wiley   +1 more source

Neuroendocrine crosstalk between sex and metabolic hormones: mechanisms and implications across the female reproductive spectrum. [PDF]

Discov Endocrinol Metab
Goulet V, Léveillé D, Li J, Fisette A.
europepmc   +1 more source

Vector‐based comparison as a novel framework for assessing multi‐endpoint clinical trials: Applications to actual data

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Multi‐endpoint clinical trials face long‐standing statistical challenges. Vector‐based comparison (VBC) decomposes endpoints into orthogonal components. Applied to five clinical trials, it reduced confidence‐interval widths by about 50%, indicating higher statistical power, without altering the clinical meaning of endpoints.
Maria Kokkali, Vangelis D. Karalis
wiley   +1 more source

Metabolic inflammation at the adipose-brain axis. [PDF]

Front Physiol
Mateus-Gomes S, Al-Sayyar A, Lobey B, Nadjar A, Rua R, Ahmad R.   +5 more
europepmc   +1 more source

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

AdipoR1-AMPK axis suppresses breast cancer across molecular subtypes via multimodal cell death pathways, including ferroptosis and apoptosis. [PDF]

Cell Death Dis
Sato S, Yamanaka T, Komori Y, Ishida M, Nakamura Y, Yamashita T, Miyagi Y.   +6 more
europepmc   +1 more source

Antiglycation of Insulin by Selected Six Bioactive Peanut Sprout Stilbenoids and Demonstration of Methylglyoxal‐Mediated Biphasic Insulin Glycation by O‐Phenylenediamine Derivatization

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Graphical abstract demonstrates 6 peanut sprout containing stilbenoids exhibiting varied structure‐activity potency in protection of insulin integrity from glycation mediated by methylglyoxal (MG), glucose and fructose. Meanwhile, MG‐mediated biphasic insulin glycation was evidenced in Tricine SDS‐PAGE analysis and supported by O‐phenylenediamine (OPD)
Po‐Chang Chiu, Shu‐Mei Lin, Yu‐Jang Li, Chih‐Yu Lo, Robin Y.‐Y. Chiou   +4 more
wiley   +1 more source

Adipokines in oral squamous cell carcinoma-a narrative overview. [PDF]

BDJ Open
Velusamy P, Mathew M, Kudva A, Chandrashekar C, Gadicherla S, Thuckanaickenpalayam Ragunathan Y, Kenniyan Kumar SC, Solomon MC.   +7 more
europepmc   +1 more source