Results 181 to 190 of about 29,601 (261)

Investigation of the Efficacy of Orientin in Streptozotocin‐Induced Type 1 Diabetes Model and Pancreatic Beta‐TC6 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Orientin, a natural flavonoid, protects against streptozotocin‐induced pancreatic β‐cell damage by suppressing NF‐κB–mediated inflammation, restoring antioxidant defense (SOD, CAT, GSH), and inhibiting apoptotic (Bax/Bcl‐2, Caspase‐3/9) and pyroptotic (Caspase‐1, IL‐1β) cell death pathways in both an in vivo type 1 diabetes mouse model and Beta‐TC6 ...
Bengul Ozdemir Sarikaya, Seyit Ali Bingol   +1 more
wiley   +1 more source

AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1. [PDF]

Mol Biol Rep
Mallardo M, Russo R, Daniele A, Chambery A, Nigro E.   +4 more
europepmc   +1 more source

The Impact of Ageing on Skeletal Muscle: Roles of Mitochondrial Dysregulation, Systemic Communication, and Exercise

Journal of Cellular Physiology, Volume 241, Issue 8, August 2026.
ABSTRACT Ageing is a major risk factor for degenerative diseases, including sarcopenia, which is characterized by a progressive loss of skeletal muscle mass and function, frailty, and is associated with increased mortality. Skeletal muscle regeneration relies on muscle stem cells and efficient communication with cellular microenvironment.
Juan Diego Hernández‐Camacho, Marielle Saclier   +1 more
wiley   +1 more source

The adiponectin receptor agonist AdipoRon alleviates lipotoxic injury in LMH cells. [PDF]

Poult Sci
Luan X, Xing X, Ma B, Wang Q, Pan Y, Zhu Z, Zu M, Zhao M, Cao Z.   +8 more
europepmc   +1 more source

Selective Small‐Molecule AdipoR1 Agonist 3‐Hydroxy Pterocarpan Salt (CDRI‐1709S) Ameliorates Skeletal Muscle Atrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle atrophy is a frequent comorbidity of metabolic disorders and chronic diseases, and despite its high prevalence, no pharmacological therapy is available, representing a major unmet clinical need. Adiponectin and its receptors are key regulators of skeletal muscle metabolism, mitochondrial function and myogenesis, yet ...
Md. Rameez Moin, Shyamal Pal, Shubhrajyoti Das, Pallavi Awasthi, Anushka Talukdar, Akhilesh Kumar, Shruti Suhas Varode, Nikhil Nikolas, Shamima Khatoon, Madhav Nilkanth Mugale, Rajdeep Guha, Sabyasachi Sanyal, Atul Goel   +12 more
wiley   +1 more source

Protection of goose adiponectin-derived peptide gADP3 on LPS-induced thymus and spleen injury in goose. [PDF]

Poult Sci
Ma B, Cao Z, Yao Z, Zheng Y, Gao M, Luan X.   +5 more
europepmc   +1 more source

Loss of Rab8a‐Dependent Tethering of Lipid Droplets to Mitochondria Contributes to Hypoxia–Reoxygenation Injury

MedComm, Volume 7, Issue 8, August 2026.
Rab8a‐dependent tethering of lipid droplets to mitochondria sustains fatty acid oxidation and cardiomyocyte metabolic flexibility under normoxia. During hypoxia/reoxygenation, Rab8a loss and PLIN5‐associated lipophagy uncouple lipid breakdown from mitochondrial utilization, driving lipotoxicity and cell death.
Jialing Tang, Nathan Joyce, Thomas Laval, Eddie Tam, Hye Kyoung Sung, Mireille Ouimet, Gary Sweeney   +6 more
wiley   +1 more source

Adipose Tissue and Central Nervous System Crosstalk: Roles in Pain and Cognitive Dysfunction. [PDF]

Biomedicines
Li J, Li Z, Chen K, Wu Y, Yang X, He Z, Xiang H.   +6 more
europepmc   +1 more source

The adiponectin receptor: Physiology and pharmacology

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018
Kadowaki, Takashi, Yamauchi, Toshimasa, Okada-Iwabu, Miki, Iwabu, Masato   +3 more
openaire   +2 more sources