Results 141 to 150 of about 1,410,707 (305)

Reassessing Perioperative Management Strategies for Phaeochromocytoma and Paraganglioma Resections

ANZ Journal of Surgery, EarlyView.
Jun Wei Chong, Simon Harper, Stephanie Manning, Rosemary M. Hall   +3 more
wiley   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Guanfacine as a potential preventive therapy for chronic migraine: a mechanistic hypothesis. [PDF]

Front Neurol
Kesayan T, Patel K.
europepmc   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Anaesthetic management of a horse with acute kidney injury

Equine Veterinary Education, EarlyView.
Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley   +1 more source

Autoantibodies targeting G protein-coupled receptors and clinical outcome after ischemic stroke (PROSCIS-B). [PDF]

J Neurol
Miesenberger AS, Arlt FA, Koschützke L, Gebert P, Heidecke H, Schulze-Forster K, Catar RA, Moll G, Harms C, Kufner A, Liman T, Prüss H, Endres M, Sperber PS.   +13 more
europepmc   +1 more source

Ovarian pain in the mare: Clinical implications of mittelschmerz and oestrus‐related behavioural abnormalities

Equine Veterinary Education, EarlyView.
Summary Mittelschmerz is a well‐recognised benign peri‐ovulatory pain syndrome in women and, by physiological analogy, may also occur in mares. In equine practice, peri‐ovulatory ovarian pain has been associated with transient discomfort, colic‐like signs and behavioural changes, although its true clinical relevance remains poorly defined.
G. Marino, V. Biondi, A. Sfacteria, G. Catone, C. Vullo   +4 more
wiley   +1 more source

Influence of adrenergic drugs and volume loading on mean systemic filling pressure in non-septic and septic sheep. [PDF]

Front Med (Lausanne)
Hahn RG.
europepmc   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

In Vitro Experimental and Computational Studies of the Vasorelaxant Effects of Quinazolin-4(3<i>H</i>)-one and Its Interaction with α1-Adrenergic Receptors. [PDF]

Curr Issues Mol Biol
Rhazi Y, Bouadid I, Guerguer F, El Mesky M, Lamssane H, Nakkabi A, Bakhouch M, Qattan MY, Alkubaisi NA, Chtita S, Aboul-Soud MAM, Giesy JP, El Yazidi M, Eddouks M.   +13 more
europepmc   +1 more source