Results 151 to 160 of about 1,410,707 (305)

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge

open access: yesThe FEBS Journal, EarlyView.
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa   +1 more
wiley   +1 more source

Alpha Kappa Alpha EAF Awards luncheon program, July 15, 2014

open access: yes, 2014
This program for the Educational Advancement Foundation (EAF) Awards luncheon given by the Alpha Kappa Alpha sorority notes the sequence of events, leaders of the EAF, and sponsors for the gathering.Archival master image scanned in reflective mode as 48 ...
Alpha Kappa Alpha
core  

Testing for Non‐Severe Heritable Platelet Function Disorders

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley   +3 more
wiley   +1 more source

The Interactions Between Acetylcholine and T‐Cells and Their Role in the Immune System: A Scoping Review

open access: yesImmunology, EarlyView.
Activated T‐cells instigate signalling events leading to the activation of transcription factors, which in turn, act on the nucleus to produce cytokines. We postulate that c‐fos is one of these transcription factors which upregulates the choline acetyltransferase gene responsible for synthesising acetylcholine (ACh).
Jarita Lay, Nicholas Manolios
wiley   +1 more source

Integrating Pharmacogenomic Testing Within the 4Ms Framework for Management of Behavioral Symptoms in Advanced Vascular Dementia: A Case Study

open access: yesJournal of the American Geriatrics Society, EarlyView.
Pharmacogenomic‐guided managment of behavioral symptoms within the 4Ms framework.
Gianna Franco   +3 more
wiley   +1 more source

Transient acute kidney injury following femoral fracture in mice : the role of sympathetic activation. [PDF]

open access: yesBone Joint Res
Oßwald K   +7 more
europepmc   +1 more source

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