Results 171 to 180 of about 1,410,707 (305)

Investigating the Link Between Objective Sleep Metrics and Cerebral Small Vessel Disease in a Population‐Based Cohort

Journal of Sleep Research, EarlyView.
ABSTRACT Cerebral small vessel disease (CSVD), a disorder that affects the cerebral microvasculature, is commonly associated with aging and may contribute to dementia and stroke. Increasing evidence suggests a link between CSVD and sleep disturbances, but the association remains poorly understood.
Mareike Ludwig, Arne Böttcher, Marvin Petersen, Felix Leonard Nägele, Maximilian Schell, Jacob Friedrich Clausen, Götz Thomalla, Ines Schäfer, Alena Haack, Christian Betz, Anna Sophie Hoffmann, Bastian Cheng   +11 more
wiley   +1 more source

Aripiprazole modulates splenic microbiota and immune response elicited by single prolonged stress in rats. [PDF]

Pharmacol Rep
Vargovic P, Tillinger A, Horvathova L, Dziewiczova L, Osacka J.   +4 more
europepmc   +1 more source

Veterinary Pharmaceutical Safety Competencies for New Graduates: Description of an Interprofessional Simulated Learning Activity

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The misuse and abuse of veterinary anesthetic and analgesic agents pose significant public health risks, particularly with the growing presence of ultrapotent opioids and other anesthetics in the illicit drug trade. In response, there is increasing emphasis on incorporating medication safety training into veterinary curricula.
Margene Anderson, Carrie Schroeder, Kristopher M. Schroeder   +2 more
wiley   +1 more source

Neural regulation in lung cancer: from mechanisms to new therapeutic perspectives. [PDF]

Clin Exp Med
Zhao J, Han Y, Li Y, Li Y, Sun Y, Bai Y, Chen J, Han C, Yan Y, Zhou C, Liu C.   +10 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Potential association between chronic alpha-1 adrenergic blockade and early epinephrine-related resuscitation profiles during cardiac arrest: a retrospective exploratory cohort study. [PDF]

Front Cardiovasc Med
Beyoğlu R, Özyiğit F.
europepmc   +1 more source

Targeting Overweight and Obesity Phenotypes for Secondary Prevention of Cardiovascular Disease: A Call to Action for the Middle East and Beyond

Obesity Reviews, EarlyView.
ABSTRACT Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause–effect relationship between OAO, CVD, and other systemic complications ...
Wael Almahmeed, Juan S. Barajas‐Gamboa, Mohammad Zubaid, Ebaa Al Ozairi, Abdullah Shehab, Khalid Al‐Rasadi, Charbel Abi Khalil, Noor Al Busaidi, Fahad Al Sindi, Zuhier Awan, Tomader Ali, Khaldoon Al‐Humood, Fatheya Al Awadi, Mohammed Al Hadad, Manal Al Kindi, Khalid Al Habib, Khalid Al Waili, Maryam Alsaeed, Adel Tash, Hani Sabbour   +19 more
wiley   +1 more source

Repetitive pressure overload: species disparities, mechanisms, and translational relevance. [PDF]

Am J Physiol Heart Circ Physiol
Spinale FG, Murray GM, Hollis F, Wood SK.   +3 more
europepmc   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Pseudoephedrine for Central Sympathetic Insufficiency. [PDF]

J Clin Neurol
Wcislo J, Posen A, Davis J.
europepmc   +1 more source