Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance
Periodontology 2000, EarlyView.Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf +7 more
wiley +1 more source
Systemic Medications as Triggers of Acute Angle-Closure Glaucoma: A Narrative Review. [PDF]
J Clin MedAlarfaj M, Qedair J.
europepmc +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Reappraising traumatic brain injury and ventilator-associated pneumonia through the brain-lung-immune-microbiome axis. [PDF]
Front NeurolMao L, Yang Z, Jiang F.
europepmc +1 more source
Veterinary Surgery, EarlyView.Abstract Objective To assess whether intranasal administration of xylometazoline hydrochloride 0.1% reduces intraoperative hemorrhage during ala‐vestibuloplasty in dogs undergoing surgical correction for brachycephalic obstructive airway syndrome (BOAS). Study design Prospective, randomized, placebo‐controlled clinical trial.
Jun‐Yan Sek +4 more
wiley +1 more source
Adrenergic receptors: a key determinant of outcomes in bacterial pneumonia and bacterial sepsis-associated acute lung injury/acute respiratory distress syndrome through participation in pulmonary innate immune response. [PDF]
Front ImmunolZeng L, Yang J, Yan J.
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract Individuals with persisting post‐concussion symptoms with physiological subtype (PPCS‐P) demonstrate exercise intolerance due to exacerbation of concussion‐like symptoms during incremental exercise. We tested the hypothesis that individuals with PPCS‐P (n = 12) would have a blunted cardiac autonomic response to face cooling compared to healthy
Phillip J. Wallace +6 more
wiley +1 more source
Cerebral haemodynamic responses to inspiratory muscle work
Experimental Physiology, EarlyView.Abstract Fatiguing inspiratory work has been shown to evoke a sympathetically mediated reflex that has systemic cardiovascular consequences, including increases in heart rate and blood pressure and a decrease in resting limb vascular conductance. Moreover, the response to this reflex appears to be attenuated in females compared with males.
Andrew H. Ramsook +8 more
wiley +1 more source
The nuclear receptor ROR-alpha is a putative novel myogenic regulator of the cardiomyocyte transcriptome, including the alpha-1A adrenergic receptor. [PDF]
Am J Physiol Heart Circ PhysiolNagalingam RS +12 more
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract The incidence and presentation of obstructive sleep apnoea, as well as hypertension and cardiovascular disease, have been reported to differ by sex. It is thus reasonable to propose mechanisms contributing to subsequent pathology differ by sex. This concept is supported from a pre‐pathological perspective, as sex differences have been observed
Dain W. Jacob +4 more
wiley +1 more source