Results 81 to 90 of about 99 (98)
Endocannabinoid signaling in stress, nausea, and vomiting
Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.Abstract Background Classical antiemetics that target the serotonin system may not be effective in treating certain nausea and vomiting conditions like cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). As a result, there is a need for better therapies to manage the symptoms of these disorders, including nausea, vomiting, and ...
Marieka V. DeVuono +2 more
wiley +1 more source
Neurogastroenterology &Motility, EarlyView.In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley +1 more source
Positive social relations, loneliness, and immune system gene regulation
Annals of the New York Academy of Sciences, EarlyView.In two studies of Korean adults, positive social relations—characterized by warmth, satisfaction, and trust—are inversely associated with conserved transcriptional response to adversity (CTRA) gene expression, independent of loneliness. Social flourishing may benefit human molecular well‐being, above and beyond the absence of social isolation or ...
Sung‐Ha Lee +4 more
wiley +1 more source
Obesity Reviews, EarlyView.ABSTRACT Background Existing evidence shows inconsistent associations between preterm birth and childhood obesity. The impact of full gestational age on the risk of childhood obesity and overweight remains unclear. Objectives This systematic scoping review aims to comprehensively explore the relationship between gestational age at birth across the ...
Yuantao Su +4 more
wiley +1 more source
Lipedema: Progress, Challenges, and the Road Ahead
Obesity Reviews, EarlyView.ABSTRACT Introduction Lipedema is a chronic and progressive disease that predominantly affects women, characterized by a disproportionate increase in subcutaneous adipose tissue (AT), particularly in the lower limbs. It is associated with significant physical disability, chronic pain, thromboembolism, and psychosocial distress.
Vincenza Cifarelli
wiley +1 more source
Visual field testing and glaucoma drug prescribing patterns in Australia
Ophthalmic and Physiological Optics, EarlyView.Abstract Purpose To examine glaucoma practice patterns in Australia, focusing on visual field test uptake and antiglaucoma drug prescribing by optometrists and ophthalmologists. Design A serial cross‐sectional study was conducted to describe visual field testing charges and compare them to changes in comprehensive eye examination charges, as well as to
Catherine L. Jan +8 more
wiley +1 more source
Orthopaedic Surgery, EarlyView.Due to the close connection between the autonomic nervous system and skeletal system, large amounts of evidence have shown that neuromodulation plays a crucial role in regulating bone metabolism. Clinically, neuromodulation has exhibited promising therapeutic effects in treating joint disorders by significantly reducing inflammation and clinical scores.
Ruihao Xia +7 more
wiley +1 more source
The heart, a secondary organ in the control of blood circulation
Experimental Physiology, Volume 110, Issue 5, Page 649-665, 1 May 2025.Abstract Circulation of the blood is a fundamental physiological function traditionally ascribed to the pressure‐generating function of the heart. However, over the past century the ‘cardiocentric’ view has been challenged by August Krogh, Ernst Starling, Arthur Guyton and others, based on haemodynamic data obtained from isolated heart preparations and
Branko Furst, José González‐Alonso
wiley +1 more source
Experimental Physiology, Volume 110, Issue 5, Page 675-685, 1 May 2025.Abstract The ability to increase cardiac output during dynamic exercise is paramount for the ability to maintain workload performance. Reflex control of the cardiovascular system during exercise is complex and multifaceted involving multiple feedforward and feedback systems.
Donal S. O'Leary, Joseph Mannozzi
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka +3 more
wiley +1 more source