Results 91 to 100 of about 2,465,843 (248)

Pregnancy modifies the α2-β-adrenergic receptor functional balance in rabbit fat cells

Journal of Lipid Research, 1999
The sympathetic nervous system controls lipolysis in fat by activation of four adrenergic receptors: β1, β2, β3, and α2. During pregnancy, maternal metabolism presents anabolic and catabolic phases, characterized by modifications of fat responsiveness to
Alain Bousquet-Mélou, Carmen Muñoz, Jean Galitzky, Michel Berlan, Max Lafontan   +4 more
doaj  

The Different Effects of Noradrenaline on Rhabdomyosarcoma and Ewing’s Sarcoma Cancer Hallmarks—Implications for Exercise Oncology

Onco
Background: Exercise has beneficial effects on cancer and its treatment, but the underlying mechanisms are poorly understood. Some studies have linked the positive impact of exercise to catecholamine signaling.
Peter Weeber, Stephanie Bremer, Jonas Haferanke, Carla Regina, Martin Schönfelder, Henning Wackerhage, Irene von Luettichau   +6 more
doaj   +1 more source

Spinal Antinociceptive Action of Amiloride and Its Interaction with Tizanidine in the Rat Formalin Test

Pain Research and Management, 2015
BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes.
Handong Ouyang, Peizong Wang, Wan Huang, Qiang Li, Bilin Nie, Weian Zeng   +5 more
doaj   +1 more source

Contribution of the sympathetic nervous system to the pathogenesis of salt-sensitive hypertension [PDF]

, 2016
Dysregulation of the sodium-chloride cotransporter (NCC) is believed to significantly impact blood pressure. Recent studies have implicated overactivity of the sympathetic nervous system as a mechanism driving renal NCC dysregulation to evoke the ...
Pazzol, Michael Lee
core   +1 more source

Gravin orchestrates protein kinase A and 2-adrenergic receptor signaling critical for synaptic plasticity and memory [PDF]

, 2012
A kinase-anchoring proteins (AKAPs) organize compartmentalized pools of protein kinase A (PKA) to enable localized signaling events within neurons. However, it is unclear which of the many expressed AKAPs in neurons target PKA to signaling complexes ...
Abel, T., Baillie, G.S., Canton, D.A., Day, J.P., Gelman, I.H., Grimes, Q., Guercio, L.A., Havekes, R., Huang, T., Luczak, V., Nie, T., Park, A.J., Scott, J.D.   +12 more
core   +2 more sources

Alveolar Epithelial β2-Adrenergic Receptors

, 2008
β2-adrenergic receptors are present throughout the lung, including the alveolar airspace, where they play an important role for regulation of the active Na+ transport needed for clearance of excess fluid out of alveolar airspace.
G. Mutlu, P. Factor
semanticscholar   +1 more source

Beta-Adrenergic Receptors and Mechanisms in Asthma: The New Long-Acting Beta-Agonists

Allergology International, 1996
The objective is to review β-adrenergic receptors and mechanisms in the immediate and late bronchial reaction in asthma and the new long-acting β-agonist.
Robert G Townley
doaj   +1 more source

Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists

Nature Neuroscience, 2015
Do sedatives engage natural sleep pathways? It is usually assumed that anesthetic-induced sedation and loss of righting reflex (LORR) arise by influencing the same circuitry to lesser or greater extents.
Zhe Zhang, V. Ferretti, İlke Güntan, A. Moro, E. Steinberg, Z. Ye, A. Zecharia, Xiao Yu, A. Vyssotski, S. Brickley, R. Yustos, Zoe E Pillidge, Edward C. Harding, W. Wisden, N. Franks   +14 more
semanticscholar   +1 more source

Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α2C Adrenergic Receptor

Cell Reports, 2019
Summary: Adrenergic G-protein-coupled receptors (GPCRs) mediate different cellular signaling pathways in the presence of endogenous catecholamines and play important roles in both physiological and pathological conditions.
Xiaoyu Chen, Yueming Xu, Lu Qu, Lijie Wu, Gye Won Han, Yu Guo, Yiran Wu, Qingtong Zhou, Qianqian Sun, Cenfeng Chu, Jie Yang, Liu Yang, Quan Wang, Shuguang Yuan, Ling Wang, Tao Hu, Houchao Tao, Yaping Sun, Yunpeng Song, Liaoyuan Hu, Zhi-Jie Liu, Raymond C. Stevens, Suwen Zhao, Dong Wu, Guisheng Zhong   +24 more
doaj  

Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation.

Proceedings of the National Academy of Sciences of the United States of America, 2001
G-protein-coupled receptors (GPCRs) have recently joined the list of cell surface receptors that dimerize. Dimerization has been shown to alter the ligand-binding, signaling, and trafficking properties of these receptors.
Bryen A. Jordan, N. Trapaidze, I. Gomes, R. Nivarthi, R. Nivarthi, L. Devi   +5 more
semanticscholar   +1 more source