Results 221 to 230 of about 171,068 (287)

Study participant impression of use and satisfaction with STS101 (dihydroergotamine nasal powder): Results from the open‐label ASCEND acute migraine study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective/Background This study was undertaken to assess participants' impression of use and satisfaction with STS101 in a long‐term, open‐label safety study. The ASCEND study assessed the safety and tolerability of STS101, an investigational drug–device combination of 5.2 mg dihydroergotamine in a single‐use nasal delivery device for the ...
Jessica Ailani, Larry Charleston IV, Shannon Strom, Detlef Albrecht, Robert Cowan   +4 more
wiley   +1 more source

The role of α₂-adrenergic mechanisms in sympathetic baroreflex control of human blood pressure. [PDF]

Am J Physiol Heart Circ Physiol
Spafford JE, Limberg JK, Harvey RE, Wiggins CC, Iannarelli NJ, Senefeld JW, Nicholson WT, Curry TB, Joyner MJ, Shoemaker JK, Baker SE, Klassen SA.   +11 more
europepmc   +1 more source

Chronically elevated sympathetic nervous system tone: A significant, common, and poorly realised contributor to cardiometabolic disease in type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Ralph A. DeFronzo
wiley   +1 more source

Global Patterns of Comorbidities Among Patients With Hidradenitis Suppurativa: A Systematic Review and Meta‐Analysis

International Journal of Dermatology, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder increasingly recognized as a systemic disease with diverse comorbidities. While several comorbid conditions are well documented, regional differences in prevalence remain unclear.
Aditya K. Gupta, Amanda Liddy, Vasiliki Economopoulos, Renata Magalhaes   +3 more
wiley   +1 more source

Molecular mechanisms and therapeutic implications of the sympathetic nervous system in bone-related disorders: a brain-bone axis perspective. [PDF]

Bone Res
Liu M, Liu Y, Yu J, Gong J, Zhao C, Liu Z.   +5 more
europepmc   +1 more source

[Adrenergic receptors].

Revista do Hospital das Clinicas, 1975
openaire   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

Neural Circuit Connections and Functions of Locus Coeruleus-Norepinephrine System. [PDF]

Int J Mol Sci
Hao M, Li F, Duan JW, Han MH.
europepmc   +1 more source

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

Beyond the heart: a review exploring non-cardiovascular effects of vasoactive agents. [PDF]

Front Pharmacol
Lan P, Chen L, Zhang C, Ni J, Yu P, Zhou J.   +5 more
europepmc   +1 more source