Results 51 to 60 of about 793,499 (319)
Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]
, 1974 T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core +1 more source
Can We Improve Vaccine Efficacy by Targeting T and B Cell Repertoire Convergence?
Frontiers in Immunology, 2019 Traditional vaccine development builds on the assumption that healthy individuals have virtually unlimited antigen recognition repertoires of receptors in B cells and T cells [the B cell receptor (BCR) and TCR respectively].
Katja Fink
doaj +1 more source
B‐cell antigen‐receptor signalling in lymphocyte development [PDF]
Immunology, 2003 SummarySignalling through the B‐cell antigen receptor (BCR) is required throughout B‐cell development and peripheral maturation. Targeted disruption of BCR components or downstream effectors indicates that specific signalling mechanisms are preferentially required for central B‐cell development, peripheral maturation and repertoire selection ...
Leo D, Wang, Marcus R, Clark
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Function of Themis2 in B Cells [PDF]
, 2015 Thymocyte-expressed molecule involved in selection 2 (Themis2) is the second member of the Themis family. Recently, the first member of the Themis family, Themis, has been reported to be part of the TCR signalling cascade and its deletion severely ...
Hartweger, H
core
B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting
Cell Reports, 2018 Summary: Antigen-dependent engagement of germinal center (GC) B cell receptors (BCRs) promotes antigen internalization and presentation for follicular helper T cells.
Jackson Steed Turner +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Carcinoembryonic Antigen Gene Family [PDF]
, 1991 The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin supergene family and can be divided into two main subgroups based on sequence comparisons.
Zimmermann, Wolfgang +2 more
core +1 more source
EBF1, PAX5, and MYC: regulation on B cell development and association with hematologic neoplasms
Frontiers in ImmunologyDuring lymphocyte development, a diverse repertoire of lymphocyte antigen receptors is produced to battle against pathogens, which is the basis of adaptive immunity.
Li Li, Daiquan Zhang, Xinmei Cao
doaj +1 more source
Nature Communications, 2016 Plasma cells produce secreted antibodies and are thought to lack expression of the membrane-bound immunoglobulins that constitute B-cell receptors. Here the authors show that IgM-expressing plasma cells maintain B-cell receptor expression and initiate ...
Pascal Blanc +17 more
doaj +1 more source